Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 422 - 426 |
| Number of pages | 5 |
| Journal | European Journal of Pharmaceutical Sciences |
| Volume | 44 |
| DOIs | |
| Publication status | Published - 2011 |
Cite this
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Chitosan nanoparticles enhance the plasma exposure of (-) -epigallocatechin gallate in mice through an enhancement in intestinal stability. / Dube, Admire; Nicolazzo, Joseph; Larson, Ian.
In: European Journal of Pharmaceutical Sciences, Vol. 44, 2011, p. 422 - 426.Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - Chitosan nanoparticles enhance the plasma exposure of (-) -epigallocatechin gallate in mice through an enhancement in intestinal stability
AU - Dube, Admire
AU - Nicolazzo, Joseph
AU - Larson, Ian
PY - 2011
Y1 - 2011
N2 - The green tea catechin (-)-epigallocatechin gallate (EGCG) has attracted significant research interest due to its beneficial therapeutic effects, which include anti-oxidant, neuro-protective and anti-cancer effects. However, the therapeutic potential of EGCG following oral consumption is limited by its poor absorption. To address this issue, EGCG has been encapsulated in chitosan-tripolyphosphate nanoparticles (CS NPs) and the oral absorption of EGCG evaluated in Swiss Outbred mice.
AB - The green tea catechin (-)-epigallocatechin gallate (EGCG) has attracted significant research interest due to its beneficial therapeutic effects, which include anti-oxidant, neuro-protective and anti-cancer effects. However, the therapeutic potential of EGCG following oral consumption is limited by its poor absorption. To address this issue, EGCG has been encapsulated in chitosan-tripolyphosphate nanoparticles (CS NPs) and the oral absorption of EGCG evaluated in Swiss Outbred mice.
UR - http://www.sciencedirect.com/science/article/pii/S0928098711003083
U2 - 10.1016/j.eps.2011.09.004
DO - 10.1016/j.eps.2011.09.004
M3 - Article
VL - 44
SP - 422
EP - 426
JO - European Journal of Pharmaceutical Sciences
JF - European Journal of Pharmaceutical Sciences
SN - 0928-0987
ER -