TY - JOUR
T1 - Chemokines and chemokine receptors in T-cell priming and Th1/Th2- mediated responses
AU - Sallusto, Federica
AU - Lanzavecchia, Antonio
AU - MacKay, Charles R.
PY - 1998/12/1
Y1 - 1998/12/1
N2 - T-cell priming occurs in the lymphoid tissue via T cell-dendritic cell interaction. Conversely, delayed-type hypersensitivity or allergic reactions can occur in any tissue, following interaction of T helper 1 (Th1) or Th2 cells with effector leukocytes. Here, Federica Sallusto and colleagues review the role played by chemokines and chemokine receptors in positioning T cells for the immune response.
AB - T-cell priming occurs in the lymphoid tissue via T cell-dendritic cell interaction. Conversely, delayed-type hypersensitivity or allergic reactions can occur in any tissue, following interaction of T helper 1 (Th1) or Th2 cells with effector leukocytes. Here, Federica Sallusto and colleagues review the role played by chemokines and chemokine receptors in positioning T cells for the immune response.
UR - http://www.scopus.com/inward/record.url?scp=0031764104&partnerID=8YFLogxK
U2 - 10.1016/S0167-5699(98)01346-2
DO - 10.1016/S0167-5699(98)01346-2
M3 - Review Article
C2 - 9864948
AN - SCOPUS:0031764104
SN - 1471-4906
VL - 19
SP - 568
EP - 574
JO - Trends in Immunology
JF - Trends in Immunology
IS - 12
ER -