Chemokines and chemokine receptors in T-cell priming and Th1/Th2- mediated responses

Federica Sallusto; Antonio Lanzavecchia; Charles R. MacKay

doi:10.1016/S0167-5699(98)01346-2

Chemokines and chemokine receptors in T-cell priming and Th1/Th2- mediated responses

Federica Sallusto, Antonio Lanzavecchia, Charles R. MacKay

Research output: Contribution to journal › Review Article › Research › peer-review

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Abstract

T-cell priming occurs in the lymphoid tissue via T cell-dendritic cell interaction. Conversely, delayed-type hypersensitivity or allergic reactions can occur in any tissue, following interaction of T helper 1 (Th1) or Th2 cells with effector leukocytes. Here, Federica Sallusto and colleagues review the role played by chemokines and chemokine receptors in positioning T cells for the immune response.

Original language	English
Pages (from-to)	568-574
Number of pages	7
Journal	Immunology Today
Volume	19
Issue number	12
DOIs	https://doi.org/10.1016/S0167-5699(98)01346-2
Publication status	Published - 1 Dec 1998
Externally published	Yes

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abstract = "T-cell priming occurs in the lymphoid tissue via T cell-dendritic cell interaction. Conversely, delayed-type hypersensitivity or allergic reactions can occur in any tissue, following interaction of T helper 1 (Th1) or Th2 cells with effector leukocytes. Here, Federica Sallusto and colleagues review the role played by chemokines and chemokine receptors in positioning T cells for the immune response.",

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AU - Lanzavecchia, Antonio

AU - MacKay, Charles R.

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AB - T-cell priming occurs in the lymphoid tissue via T cell-dendritic cell interaction. Conversely, delayed-type hypersensitivity or allergic reactions can occur in any tissue, following interaction of T helper 1 (Th1) or Th2 cells with effector leukocytes. Here, Federica Sallusto and colleagues review the role played by chemokines and chemokine receptors in positioning T cells for the immune response.

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Chemokines and chemokine receptors in T-cell priming and Th1/Th2- mediated responses

Abstract

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