Chemical signature of ecstasy volatiles by comprehensive two-dimensional gas chromatography

Blagoj Mitrevski, Biljana Veleska, Erwan Engel, Paul Wynne, Shin-Miin Song, Philip Marriott

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Abstract

A method for ecstasy volatiles a??signaturea?? analysis based on two-dimensional gas chromatography separation and time-of-flight mass spectrometry detection (GC ?? GC-TOFMS) is presented. Organic impurity volatiles were extracted by head space solid phase microextraction (HS-SPME). The final column phase choice of the four different column combinations tested was a low-polarity 5 phenyl polysilphenylene-siloxane coupled with a polyethylene glycol phase, which best displayed the complex impurity profile. Second dimension (2D) retention time reproducibility was found to be about 1 RSD, and area reproducibility of SPME sampling was just over 5 RSD for compounds with S/N ratio of about 100.
Original languageEnglish
Pages (from-to)11 - 20
Number of pages10
JournalForensic Science International
Volume209
Issue number1-3
DOIs
Publication statusPublished - 2011
Externally publishedYes

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