TY - JOUR
T1 - Chemical signature of ecstasy volatiles by comprehensive two-dimensional gas chromatography
AU - Mitrevski, Blagoj
AU - Veleska, Biljana
AU - Engel, Erwan
AU - Wynne, Paul
AU - Song, Shin-Miin
AU - Marriott, Philip
PY - 2011
Y1 - 2011
N2 - A method for ecstasy volatiles a??signaturea?? analysis based on two-dimensional gas chromatography separation and time-of-flight mass spectrometry detection (GC ?? GC-TOFMS) is presented. Organic impurity volatiles were extracted by head space solid phase microextraction (HS-SPME). The final column phase choice of the four different column combinations tested was a low-polarity 5 phenyl polysilphenylene-siloxane coupled with a polyethylene glycol phase, which best displayed the complex impurity profile. Second dimension (2D) retention time reproducibility was found to be about 1 RSD, and area reproducibility of SPME sampling was just over 5 RSD for compounds with S/N ratio of about 100.
AB - A method for ecstasy volatiles a??signaturea?? analysis based on two-dimensional gas chromatography separation and time-of-flight mass spectrometry detection (GC ?? GC-TOFMS) is presented. Organic impurity volatiles were extracted by head space solid phase microextraction (HS-SPME). The final column phase choice of the four different column combinations tested was a low-polarity 5 phenyl polysilphenylene-siloxane coupled with a polyethylene glycol phase, which best displayed the complex impurity profile. Second dimension (2D) retention time reproducibility was found to be about 1 RSD, and area reproducibility of SPME sampling was just over 5 RSD for compounds with S/N ratio of about 100.
UR - http://www.sciencedirect.com/science/article/pii/S0379073810005098
U2 - 10.1016/j.forsciint.2010.11.008
DO - 10.1016/j.forsciint.2010.11.008
M3 - Article
SN - 0379-0738
VL - 209
SP - 11
EP - 20
JO - Forensic Science International
JF - Forensic Science International
IS - 1-3
ER -