Chemical analysis of acoustically levitated drops by Raman spectroscopy

Rudolf Tuckermann, Ljiljana Puskar, Mahta Zavabeti, Ryo Motoji Sekine, Donald McNaughton

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38 Citations (Scopus)


An experimental apparatus combining Raman spectroscopy with acoustic levitation, Raman acoustic levitation spectroscopy (RALS), is investigated in the field of physical and chemical analytics. Whereas acoustic levitation enables the contactless handling of microsized samples, Raman spectroscopy offers the advantage of a noninvasive method without complex sample preparation. After carrying out some systematic tests to probe the sensitivity of the technique to drop size, shape, and position, RALS has been successfully applied in monitoring sample dilution and preconcentration, evaporation, crystallization, an acid–base reaction, and analytes in a surface-enhanced Raman spectroscopy colloidal suspension.
Original languageEnglish
Pages (from-to)1433 - 1441
Number of pages9
JournalAnalytical and Bioanalytical Chemistry
Publication statusPublished - 2009

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