Charged extracellular residues, conserved throughout a G-protein-coupled receptor family, are required for ligand binding, receptor activation and cell-surface expression

Stuart R Hawtin; John Watson Simms; Matthew Conner; Zoe Lawson; Rosemary A Parslow; Julie Trim; Andrew Sheppard; Mark Wheatley

doi:10.1074/jbc.M607639200

Charged extracellular residues, conserved throughout a G-protein-coupled receptor family, are required for ligand binding, receptor activation and cell-surface expression

Stuart R Hawtin, John Watson Simms, Matthew Conner, Zoe Lawson, Rosemary A Parslow, Julie Trim, Andrew Sheppard, Mark Wheatley

Pharmacology

Research output: Contribution to journal › Article › Research › peer-review

41 Citations (Scopus)

Original language	English
Pages (from-to)	38478 - 38488
Number of pages	11
Journal	Journal of Biological Chemistry
Volume	281
Issue number	50
DOIs	https://doi.org/10.1074/jbc.M607639200
Publication status	Published - 2006

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10.1074/jbc.M607639200

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Hawtin, S. R., Simms, J. W., Conner, M., Lawson, Z., Parslow, R. A., Trim, J., Sheppard, A., & Wheatley, M. (2006). Charged extracellular residues, conserved throughout a G-protein-coupled receptor family, are required for ligand binding, receptor activation and cell-surface expression. Journal of Biological Chemistry, 281(50), 38478 - 38488. https://doi.org/10.1074/jbc.M607639200

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title = "Charged extracellular residues, conserved throughout a G-protein-coupled receptor family, are required for ligand binding, receptor activation and cell-surface expression",

author = "Hawtin, {Stuart R} and Simms, {John Watson} and Matthew Conner and Zoe Lawson and Parslow, {Rosemary A} and Julie Trim and Andrew Sheppard and Mark Wheatley",

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Hawtin, SR, Simms, JW, Conner, M, Lawson, Z, Parslow, RA, Trim, J, Sheppard, A & Wheatley, M 2006, 'Charged extracellular residues, conserved throughout a G-protein-coupled receptor family, are required for ligand binding, receptor activation and cell-surface expression', Journal of Biological Chemistry, vol. 281, no. 50, pp. 38478 - 38488. https://doi.org/10.1074/jbc.M607639200

Charged extracellular residues, conserved throughout a G-protein-coupled receptor family, are required for ligand binding, receptor activation and cell-surface expression. / Hawtin, Stuart R; Simms, John Watson; Conner, Matthew et al.
In: Journal of Biological Chemistry, Vol. 281, No. 50, 2006, p. 38478 - 38488.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Charged extracellular residues, conserved throughout a G-protein-coupled receptor family, are required for ligand binding, receptor activation and cell-surface expression

AU - Hawtin, Stuart R

AU - Simms, John Watson

AU - Conner, Matthew

AU - Lawson, Zoe

AU - Parslow, Rosemary A

AU - Trim, Julie

AU - Sheppard, Andrew

AU - Wheatley, Mark

PY - 2006

Y1 - 2006

U2 - 10.1074/jbc.M607639200

DO - 10.1074/jbc.M607639200

M3 - Article

SN - 0021-9258

VL - 281

SP - 38478

EP - 38488

JO - Journal of Biological Chemistry

JF - Journal of Biological Chemistry

IS - 50

ER -