Characterization of poly(2-oxazoline) homo- and copolymers by liquid chromatography at critical conditions

Anja Baumgaertel, Christine Weber, Nicole Fritz, Grit Festag, Esra Altuntaş, Kristian Kempe, Richard Hoogenboom, Ulrich S. Schubert

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

Abstract

In this study liquid chromatography at critical conditions for poly(2-ethyl-2-oxazoline)s (PEtOx) has been performed for the first time in order to analyze functional PEtOx homopolymers and block copolymers. Besides the verification of the critical point of adsorption with two series of ester end group functionalized PEtOx homopolymers, to evaluate the effect of both the chain length dependence and the end group polarity, using a cyano column with a solvent combination of 2-propanol and water, also two-dimensional liquid chromatography (2D-LC) has been applied for a poly(2-oxazoline) block copolymer. The combined characterization techniques provided further information about the polymerization procedure with regard to the formation of side-products by separation of the block copolymer from the corresponding homopolymer impurities. In addition, hyphenation of LCCC with MALDI-TOF MS and ESI-Q-TOF tandem mass spectrometry verified the obtained results.

Original languageEnglish
Pages (from-to)8370-8378
Number of pages9
JournalJournal of Chromatography A
Volume1218
Issue number46
DOIs
Publication statusPublished - 18 Nov 2011
Externally publishedYes

Keywords

  • Cationic ring-opening polymerization (CROP)
  • ESI-Q-TOF MS
  • Liquid chromatography at critical conditions (LCCC)
  • MALDI-TOF MS
  • Poly(2-oxazoline)s
  • Two-dimensional liquid chromatography (2D-LC)

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