Characterising absorption and health-related properties of phytochemicals extracted from Malaysian palm fruit biomass after oil extraction

Research output: Contribution to journalArticleResearchpeer-review

Abstract

After extraction of oil, palm fruit biomass contains a rich source of water-soluble phytochemicals (PCs) with proven bioactivity in regulating oxidative stress and inflammation (OSI). For optimal bioefficacy, the pharmacokinetic plasma peak (Tmax) should be bio-matched with the onset of OSI, which can be predicted from the Phytochemical Absorption Prediction (PCAP) model and methodology. Predicted absorption and potential for regulation of OSI by measures of total phenolic content, antioxidant capacity and hydrogen peroxide production capacity, were applied to characterise eight extracts from mesocarp fibre and kernel shells of oil-depleted palm fruits. Results indicated post-consumption absorption Tmax ranges of 0.5–12 h and 2–6 h for intake in liquid and solid forms, respectively, and generally high antioxidant activity, of palm fruit PCs. The research supports that PC extracts of palm fruit biomass have broad potential uses for human health as dietary antioxidants in foods, supplements or functional beverages.
Original languageEnglish
Number of pages31
JournalFood & Function
DOIs
Publication statusAccepted/In press - 2020

Cite this

@article{e5bb3adc55d74c93bd331b8d7f73524b,
title = "Characterising absorption and health-related properties of phytochemicals extracted from Malaysian palm fruit biomass after oil extraction",
abstract = "After extraction of oil, palm fruit biomass contains a rich source of water-soluble phytochemicals (PCs) with proven bioactivity in regulating oxidative stress and inflammation (OSI). For optimal bioefficacy, the pharmacokinetic plasma peak (Tmax) should be bio-matched with the onset of OSI, which can be predicted from the Phytochemical Absorption Prediction (PCAP) model and methodology. Predicted absorption and potential for regulation of OSI by measures of total phenolic content, antioxidant capacity and hydrogen peroxide production capacity, were applied to characterise eight extracts from mesocarp fibre and kernel shells of oil-depleted palm fruits. Results indicated post-consumption absorption Tmax ranges of 0.5–12 h and 2–6 h for intake in liquid and solid forms, respectively, and generally high antioxidant activity, of palm fruit PCs. The research supports that PC extracts of palm fruit biomass have broad potential uses for human health as dietary antioxidants in foods, supplements or functional beverages.",
author = "Sophie Selby-Pham and Siow, {Lee Fong} and Bennett, {Louise E.}",
year = "2020",
doi = "10.1039/C9FO01149H",
language = "English",
journal = "Food & Function",
issn = "2042-650X",
publisher = "The Royal Society of Chemistry",

}

TY - JOUR

T1 - Characterising absorption and health-related properties of phytochemicals extracted from Malaysian palm fruit biomass after oil extraction

AU - Selby-Pham, Sophie

AU - Siow, Lee Fong

AU - Bennett, Louise E.

PY - 2020

Y1 - 2020

N2 - After extraction of oil, palm fruit biomass contains a rich source of water-soluble phytochemicals (PCs) with proven bioactivity in regulating oxidative stress and inflammation (OSI). For optimal bioefficacy, the pharmacokinetic plasma peak (Tmax) should be bio-matched with the onset of OSI, which can be predicted from the Phytochemical Absorption Prediction (PCAP) model and methodology. Predicted absorption and potential for regulation of OSI by measures of total phenolic content, antioxidant capacity and hydrogen peroxide production capacity, were applied to characterise eight extracts from mesocarp fibre and kernel shells of oil-depleted palm fruits. Results indicated post-consumption absorption Tmax ranges of 0.5–12 h and 2–6 h for intake in liquid and solid forms, respectively, and generally high antioxidant activity, of palm fruit PCs. The research supports that PC extracts of palm fruit biomass have broad potential uses for human health as dietary antioxidants in foods, supplements or functional beverages.

AB - After extraction of oil, palm fruit biomass contains a rich source of water-soluble phytochemicals (PCs) with proven bioactivity in regulating oxidative stress and inflammation (OSI). For optimal bioefficacy, the pharmacokinetic plasma peak (Tmax) should be bio-matched with the onset of OSI, which can be predicted from the Phytochemical Absorption Prediction (PCAP) model and methodology. Predicted absorption and potential for regulation of OSI by measures of total phenolic content, antioxidant capacity and hydrogen peroxide production capacity, were applied to characterise eight extracts from mesocarp fibre and kernel shells of oil-depleted palm fruits. Results indicated post-consumption absorption Tmax ranges of 0.5–12 h and 2–6 h for intake in liquid and solid forms, respectively, and generally high antioxidant activity, of palm fruit PCs. The research supports that PC extracts of palm fruit biomass have broad potential uses for human health as dietary antioxidants in foods, supplements or functional beverages.

U2 - 10.1039/C9FO01149H

DO - 10.1039/C9FO01149H

M3 - Article

JO - Food & Function

JF - Food & Function

SN - 2042-650X

ER -