Charactering airborne allergens and human allergic responses in a university history museum

Yan Wu, Maosheng Yao, Victor W.C. Chang

Research output: Chapter in Book/Report/Conference proceedingConference PaperOther

Abstract

We aimed to quantify concentrations of airborne allergens in a university history museum where staff self-reported the incidence of allergic responses. We used SKC BioSamplers to collect air samples and enzyme-linked immunosorbent assay (ELISA) to quantify allergens. We also collected blood sera from museum staff and tested allergen-specific IgE levels in human blood sera with a radioallergosorbent test. Results showed that the concentrations of airborne fungal allergens Alt a 1 ranged from 181 to 242 ng/m3 and Asp f 1 ranged from 200 to 605 ng/m3, much higher than levels outdoors. For dust mite allergens, the highest indoor concentrations were 79 ng/m3 for Der f 1 and 84 ng/m3 for Der p 1, slightly higher than outdoor concentrations. High fungal allergen-specific IgE levels present in blood sera suggest that occupants may have had allergies caused by fungal allergens. Data from this work indicate that these aeroallergens were not only detectable but also with high levels in the museum and their abundance may constitute an important inhalation risk for occupants.

Original languageEnglish
Title of host publicationProceedings of the Healthy Buildings 2015: America Conference - Innovation in a Time of Energy Uncertainty and Climate Adaptation
Pages489-492
Number of pages4
Publication statusPublished - 2015
Externally publishedYes
EventHealthy Buildings 2015: America Conference - Innovation in a Time of Energy Uncertainty and Climate Adaptation - Boulder, United States of America
Duration: 19 Jul 201522 Jul 2015

Conference

ConferenceHealthy Buildings 2015
Abbreviated titleHB 2015
CountryUnited States of America
CityBoulder
Period19/07/1522/07/15

Keywords

  • Airborne allergens
  • Alt a 1
  • Asp f 1
  • Dust mite allergens
  • Ig E

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