Changes in satiety, supra- and infraband transit, and gastric emptying following laparoscopic adjustable gastric banding: A prospective follow-up study

Paul Burton, Kenneth Yap, Wendy Brown, Cheryl Laurie, Matthew O'Donnell, Geoffrey Hebbard, Victor Kalff, Paul O'Brien

Research output: Contribution to journalArticleResearchpeer-review

35 Citations (Scopus)

Abstract

Background Laparoscopic adjustable gastric banding (LAGB) induces and sustains weight loss, likely by activating the peripheral satiety mechanism. Recent data suggests that food is not retained above the optimally adjusted LAGB, suggesting that an alternate mechanism is inducing satiety. How transit and gastric emptying change following LAGB and correlate with satiety and weight loss have not been adequately defined. Methods LAGB patients underwent preoperative and 12-month follow-up nuclear scintigraphic assessments of esophageal transit and gastric emptying. A new technique that allowed the calculation of emptying times and transit through the supra- and infraband compartments was used to assess emptying and transit patterns postoperatively. Conclusions Weight loss, satiety, and early satiation following LAGB were associated with briefly delayed bolus transit into the infraband stomach. Retention of the semisolid meal above the LAGB was not observed. This is further evidence that suggests satiety develops following LAGB without physical restriction of meal size.
Original languageEnglish
Pages (from-to)217 - 223
Number of pages7
JournalObesity Surgery
Volume21
Issue number2
DOIs
Publication statusPublished - 2011

Cite this

@article{99e9e6d687874c0ebdf69779a0a8bdc1,
title = "Changes in satiety, supra- and infraband transit, and gastric emptying following laparoscopic adjustable gastric banding: A prospective follow-up study",
abstract = "Background Laparoscopic adjustable gastric banding (LAGB) induces and sustains weight loss, likely by activating the peripheral satiety mechanism. Recent data suggests that food is not retained above the optimally adjusted LAGB, suggesting that an alternate mechanism is inducing satiety. How transit and gastric emptying change following LAGB and correlate with satiety and weight loss have not been adequately defined. Methods LAGB patients underwent preoperative and 12-month follow-up nuclear scintigraphic assessments of esophageal transit and gastric emptying. A new technique that allowed the calculation of emptying times and transit through the supra- and infraband compartments was used to assess emptying and transit patterns postoperatively. Conclusions Weight loss, satiety, and early satiation following LAGB were associated with briefly delayed bolus transit into the infraband stomach. Retention of the semisolid meal above the LAGB was not observed. This is further evidence that suggests satiety develops following LAGB without physical restriction of meal size.",
author = "Paul Burton and Kenneth Yap and Wendy Brown and Cheryl Laurie and Matthew O'Donnell and Geoffrey Hebbard and Victor Kalff and Paul O'Brien",
year = "2011",
doi = "10.1007/s11695-010-0312-y",
language = "English",
volume = "21",
pages = "217 -- 223",
journal = "Obesity Surgery",
issn = "0960-8923",
publisher = "Springer-Verlag London Ltd.",
number = "2",

}

Changes in satiety, supra- and infraband transit, and gastric emptying following laparoscopic adjustable gastric banding: A prospective follow-up study. / Burton, Paul; Yap, Kenneth; Brown, Wendy; Laurie, Cheryl; O'Donnell, Matthew; Hebbard, Geoffrey; Kalff, Victor; O'Brien, Paul.

In: Obesity Surgery, Vol. 21, No. 2, 2011, p. 217 - 223.

Research output: Contribution to journalArticleResearchpeer-review

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T1 - Changes in satiety, supra- and infraband transit, and gastric emptying following laparoscopic adjustable gastric banding: A prospective follow-up study

AU - Burton, Paul

AU - Yap, Kenneth

AU - Brown, Wendy

AU - Laurie, Cheryl

AU - O'Donnell, Matthew

AU - Hebbard, Geoffrey

AU - Kalff, Victor

AU - O'Brien, Paul

PY - 2011

Y1 - 2011

N2 - Background Laparoscopic adjustable gastric banding (LAGB) induces and sustains weight loss, likely by activating the peripheral satiety mechanism. Recent data suggests that food is not retained above the optimally adjusted LAGB, suggesting that an alternate mechanism is inducing satiety. How transit and gastric emptying change following LAGB and correlate with satiety and weight loss have not been adequately defined. Methods LAGB patients underwent preoperative and 12-month follow-up nuclear scintigraphic assessments of esophageal transit and gastric emptying. A new technique that allowed the calculation of emptying times and transit through the supra- and infraband compartments was used to assess emptying and transit patterns postoperatively. Conclusions Weight loss, satiety, and early satiation following LAGB were associated with briefly delayed bolus transit into the infraband stomach. Retention of the semisolid meal above the LAGB was not observed. This is further evidence that suggests satiety develops following LAGB without physical restriction of meal size.

AB - Background Laparoscopic adjustable gastric banding (LAGB) induces and sustains weight loss, likely by activating the peripheral satiety mechanism. Recent data suggests that food is not retained above the optimally adjusted LAGB, suggesting that an alternate mechanism is inducing satiety. How transit and gastric emptying change following LAGB and correlate with satiety and weight loss have not been adequately defined. Methods LAGB patients underwent preoperative and 12-month follow-up nuclear scintigraphic assessments of esophageal transit and gastric emptying. A new technique that allowed the calculation of emptying times and transit through the supra- and infraband compartments was used to assess emptying and transit patterns postoperatively. Conclusions Weight loss, satiety, and early satiation following LAGB were associated with briefly delayed bolus transit into the infraband stomach. Retention of the semisolid meal above the LAGB was not observed. This is further evidence that suggests satiety develops following LAGB without physical restriction of meal size.

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