Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases

Lars Fugger; Lise Torp Jensen; Jamie Rossjohn

doi:10.1016/j.cell.2020.03.007

Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases

Lars Fugger, Lise Torp Jensen, Jamie Rossjohn

Research output: Contribution to journal › Review Article › Research › peer-review

217 Citations (Scopus)

Abstract

Autoimmune diseases are a result of the immune system being misdirected toward its host and have major and increasing unmet clinical needs. In general, present therapies are broadly acting and non-disease specific; consequently, they are associated with numerous side effects. Precise and early intervention strategies are urgently needed. We highlight the challenges, progress, and prospects in achieving these goals.

Original language	English
Pages (from-to)	63-80
Number of pages	18
Journal	Cell
Volume	181
Issue number	1
DOIs	https://doi.org/10.1016/j.cell.2020.03.007
Publication status	Published - 2 Apr 2020

Access to Document

10.1016/j.cell.2020.03.007

Cite this

@article{0b38021d5d064c8c85349a10e10c9d43,

title = "Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases",

abstract = "Autoimmune diseases are a result of the immune system being misdirected toward its host and have major and increasing unmet clinical needs. In general, present therapies are broadly acting and non-disease specific; consequently, they are associated with numerous side effects. Precise and early intervention strategies are urgently needed. We highlight the challenges, progress, and prospects in achieving these goals.",

author = "Lars Fugger and Jensen, {Lise Torp} and Jamie Rossjohn",

year = "2020",

month = apr,

day = "2",

doi = "10.1016/j.cell.2020.03.007",

language = "English",

volume = "181",

pages = "63--80",

journal = "Cell",

issn = "0092-8674",

publisher = "Cell Press",

number = "1",

}

TY - JOUR

T1 - Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases

AU - Fugger, Lars

AU - Jensen, Lise Torp

AU - Rossjohn, Jamie

PY - 2020/4/2

Y1 - 2020/4/2

N2 - Autoimmune diseases are a result of the immune system being misdirected toward its host and have major and increasing unmet clinical needs. In general, present therapies are broadly acting and non-disease specific; consequently, they are associated with numerous side effects. Precise and early intervention strategies are urgently needed. We highlight the challenges, progress, and prospects in achieving these goals.

AB - Autoimmune diseases are a result of the immune system being misdirected toward its host and have major and increasing unmet clinical needs. In general, present therapies are broadly acting and non-disease specific; consequently, they are associated with numerous side effects. Precise and early intervention strategies are urgently needed. We highlight the challenges, progress, and prospects in achieving these goals.

UR - http://www.scopus.com/inward/record.url?scp=85082423259&partnerID=8YFLogxK

U2 - 10.1016/j.cell.2020.03.007

DO - 10.1016/j.cell.2020.03.007

M3 - Review Article

AN - SCOPUS:85082423259

SN - 0092-8674

VL - 181

SP - 63

EP - 80

JO - Cell

JF - Cell

IS - 1

ER -

Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases

Abstract

Access to Document

Other files and links

ARC Centre of Excellence in Advanced Molecular Imaging

Cite this

Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases

Abstract

Access to Document

Other files and links

Projects

ARC Centre of Excellence in Advanced Molecular Imaging

Cite this