TY - JOUR
T1 - CFD modeling of an ultrasonic separator for the removal of lipid particles from pericardial suction blood
AU - Trippa, Giuliana
AU - Ventikos, Yiannis
AU - Taggart, David P.
AU - Coussios, Constantin C.
N1 - Funding Information:
Manuscript received January 18, 2010; revised April 13, 2010; accepted April 13, 2010. Date of publication July 29, 2010; date of current version January 21, 2011. This work was supported by the British Heart Foundation under Grant PG/07/010/22307. Asterisk indicates corresponding author. *G. Trippa is with the Department of Engineering Science, Institute of Biomedical Engineering, University of Oxford, Oxford, OX3 7DQ, U.K. (e-mail: [email protected]).
PY - 2011/2
Y1 - 2011/2
N2 - A computational fluid dynamics (CFD) model is presented to simulate the removal of lipid particles from blood using a novel ultrasonic quarter-wavelength separator. The LagrangianEulerian CFD model accounts for conservation of mass and momentum, for the presence of lipid particles of a range of diameters, for the acoustic force as experienced by the particles in the blood, as well as for gravity and other particlefluid interaction forces. In the separator, the liquid flows radially inward within a fluid chamber formed between a disc-shaped transducer and a disc-shaped reflector. Following separation of the lipid particles, blood exits the separator axially through a central opening on the disc-shaped reflector. Separator diameters studied varied between 12 and 18 cm, and gap sizes between the discs of 600 μm, 800 μm and 1 μmm were considered. Results show a strong effect of residence time of the particles within the chamber on the separation performance. Different separator configurations were identified, which could give a lipid removal performance of 95 or higher when processing 62.5 cm3/min of blood. The developed model provides a design method for the selection of geometric and operating parameters for the ultrasonic separator.
AB - A computational fluid dynamics (CFD) model is presented to simulate the removal of lipid particles from blood using a novel ultrasonic quarter-wavelength separator. The LagrangianEulerian CFD model accounts for conservation of mass and momentum, for the presence of lipid particles of a range of diameters, for the acoustic force as experienced by the particles in the blood, as well as for gravity and other particlefluid interaction forces. In the separator, the liquid flows radially inward within a fluid chamber formed between a disc-shaped transducer and a disc-shaped reflector. Following separation of the lipid particles, blood exits the separator axially through a central opening on the disc-shaped reflector. Separator diameters studied varied between 12 and 18 cm, and gap sizes between the discs of 600 μm, 800 μm and 1 μmm were considered. Results show a strong effect of residence time of the particles within the chamber on the separation performance. Different separator configurations were identified, which could give a lipid removal performance of 95 or higher when processing 62.5 cm3/min of blood. The developed model provides a design method for the selection of geometric and operating parameters for the ultrasonic separator.
KW - Computational fluid dynamics (CFD)
KW - lipid particles
KW - radial flow
KW - separation performance
KW - ultrasonic separator
UR - http://www.scopus.com/inward/record.url?scp=79551540940&partnerID=8YFLogxK
U2 - 10.1109/TBME.2010.2061845
DO - 10.1109/TBME.2010.2061845
M3 - Article
C2 - 20679023
AN - SCOPUS:79551540940
SN - 0018-9294
VL - 58
SP - 282
EP - 290
JO - IEEE Transactions on Biomedical Engineering
JF - IEEE Transactions on Biomedical Engineering
IS - 2
M1 - 5530362
ER -