Cellular uptake and anticancer effects of mucoadhesive curcumin-containing chitosan nanoparticles

Alice Lay Chuah; Clive J Roberts; Nashiru Billa; Syahril Abdullah; Rozita Rosli

doi:10.1016/j.colsurfb.2014.01.007

Cellular uptake and anticancer effects of mucoadhesive curcumin-containing chitosan nanoparticles

Alice Lay Chuah, Clive J Roberts, Nashiru Billa, Syahril Abdullah, Rozita Rosli

Research output: Contribution to journal › Article › Research › peer-review

85 Citations (Scopus)

Abstract

Curcumin, which is derived from turmeric has gained much attention in recent years for its anticancer activities against various cancers. However,due to its poor absorption, rapid metabolism and elimination, curcumin has a very low oral bioavailability.

Original language	English
Pages (from-to)	228 - 236
Number of pages	9
Journal	Colloids and Surfaces B: Biointerfaces
Volume	116
DOIs	https://doi.org/10.1016/j.colsurfb.2014.01.007
Publication status	Published - 2014

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10.1016/j.colsurfb.2014.01.007

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Cite this

@article{0d5a709048a14030908efa9825b54e49,

title = "Cellular uptake and anticancer effects of mucoadhesive curcumin-containing chitosan nanoparticles",

abstract = "Curcumin, which is derived from turmeric has gained much attention in recent years for its anticancer activities against various cancers. However,due to its poor absorption, rapid metabolism and elimination, curcumin has a very low oral bioavailability.",

author = "Chuah, {Alice Lay} and Roberts, {Clive J} and Nashiru Billa and Syahril Abdullah and Rozita Rosli",

year = "2014",

doi = "10.1016/j.colsurfb.2014.01.007",

language = "English",

volume = "116",

pages = "228 -- 236",

journal = "Colloids and Surfaces B: Biointerfaces",

issn = "0927-7765",

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T1 - Cellular uptake and anticancer effects of mucoadhesive curcumin-containing chitosan nanoparticles

AU - Chuah, Alice Lay

AU - Roberts, Clive J

AU - Billa, Nashiru

AU - Abdullah, Syahril

AU - Rosli, Rozita

PY - 2014

Y1 - 2014

N2 - Curcumin, which is derived from turmeric has gained much attention in recent years for its anticancer activities against various cancers. However,due to its poor absorption, rapid metabolism and elimination, curcumin has a very low oral bioavailability.

AB - Curcumin, which is derived from turmeric has gained much attention in recent years for its anticancer activities against various cancers. However,due to its poor absorption, rapid metabolism and elimination, curcumin has a very low oral bioavailability.

UR - http://www.sciencedirect.com/science/article/pii/S0927776514000083

U2 - 10.1016/j.colsurfb.2014.01.007

DO - 10.1016/j.colsurfb.2014.01.007

M3 - Article

VL - 116

SP - 228

EP - 236

JO - Colloids and Surfaces B: Biointerfaces

JF - Colloids and Surfaces B: Biointerfaces

SN - 0927-7765

ER -