Cell directional migration and oriented division on three-dimensional laser-induced periodic surface structures on polystyrene

Xuefeng Wang, Christian Andre Ohlin, Qinghua Lu, Jun Hu

Research output: Contribution to journalArticleResearchpeer-review

49 Citations (Scopus)


The extracellular matrix in animal tissues usually provides a three-dimensional structural support to cells in addition to performing various other important functions. In the present study, wavy submicrometer laser-irradiated periodic surface structures (LIPSS) were produced on a smooth polystyrene film by polarized laser irradiation with a wavelength of 266 nm. Rat C6 glioma cells exhibited directional migration and oriented division on laser-irradiated polystyrene, which was parallel to the direction of LIPSS.
Original languageEnglish
Pages (from-to)2049 - 2059
Number of pages11
Issue number13
Publication statusPublished - 2008
Externally publishedYes

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