Cassia alata and Its Phytochemicals: A Promising Natural Strategy in Wound Recovery

Jing Wen Keng; Sue Kei Lee; Sze Huey Sang; Kai Bin Liew; Swee Sen Teo; Wan Mastura Shaik Mohamed Mossadeq; Sek Chuen Chow; Gabriel Akyirem Akowuah; Siew Keah Lee; Chun Wai Mai; Yik Ling Chew

doi:10.3390/sci6020034

Cassia alata and Its Phytochemicals: A Promising Natural Strategy in Wound Recovery

Jing Wen Keng, Sue Kei Lee, Sze Huey Sang, Kai Bin Liew, Swee Sen Teo, Wan Mastura Shaik Mohamed Mossadeq, Sek Chuen Chow, Gabriel Akyirem Akowuah, Siew Keah Lee, Chun Wai Mai, Yik Ling Chew

Research output: Contribution to journal › Review Article › Research › peer-review

7 Citations (Scopus)

Abstract

Cassia alata, a traditional herb with a global presence, is renowned for its anti-inflammatory, antibacterial, and antifungal properties, making it a go-to remedy for skin ailments. While it has demonstrated wound healing capabilities in both in vitro and in vivo studies, the precise mechanisms remain elusive. This review aims to highlight its key phytochemicals, their effects, and the mechanism of action. The compounds that have been reviewed and discussed include kaempferol, apigenin, quercetin, rhein, and rutin. These polyphenols play important roles in normal and impaired wound healing processes, encompassing hemostasis, inflammation, proliferation, and tissue remodeling.

Original language	English
Article number	34
Number of pages	23
Journal	Sci
Volume	6
Issue number	2
DOIs	https://doi.org/10.3390/sci6020034
Publication status	Published - Jun 2024

Keywords

antimicrobial
antioxidant
apigenin
Cassia alata
inflammation
kaempferol
quercetin
rhein
rutin
wound healing

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title = "Cassia alata and Its Phytochemicals: A Promising Natural Strategy in Wound Recovery",

abstract = "Cassia alata, a traditional herb with a global presence, is renowned for its anti-inflammatory, antibacterial, and antifungal properties, making it a go-to remedy for skin ailments. While it has demonstrated wound healing capabilities in both in vitro and in vivo studies, the precise mechanisms remain elusive. This review aims to highlight its key phytochemicals, their effects, and the mechanism of action. The compounds that have been reviewed and discussed include kaempferol, apigenin, quercetin, rhein, and rutin. These polyphenols play important roles in normal and impaired wound healing processes, encompassing hemostasis, inflammation, proliferation, and tissue remodeling.",

keywords = "antimicrobial, antioxidant, apigenin, Cassia alata, inflammation, kaempferol, quercetin, rhein, rutin, wound healing",

author = "Keng, \{Jing Wen\} and Lee, \{Sue Kei\} and Sang, \{Sze Huey\} and Liew, \{Kai Bin\} and Teo, \{Swee Sen\} and Mossadeq, \{Wan Mastura Shaik Mohamed\} and Chow, \{Sek Chuen\} and Akowuah, \{Gabriel Akyirem\} and Lee, \{Siew Keah\} and Mai, \{Chun Wai\} and Chew, \{Yik Ling\}",

note = "Funding Information: The authors would like to acknowledge the support of the Fundamental Research Grant Scheme (FRGS) (FRGS/1/2021/STG02/UCSI/02/1) from the Ministry of Higher Education Malaysia and UCSI University Research Excellence \& Innovation Grant (REIG) (REIG-FPS-2023/037). Publisher Copyright: {\textcopyright} 2024 by the authors.",

year = "2024",

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doi = "10.3390/sci6020034",

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TY - JOUR

T1 - Cassia alata and Its Phytochemicals

T2 - A Promising Natural Strategy in Wound Recovery

AU - Keng, Jing Wen

AU - Lee, Sue Kei

AU - Sang, Sze Huey

AU - Liew, Kai Bin

AU - Teo, Swee Sen

AU - Mossadeq, Wan Mastura Shaik Mohamed

AU - Chow, Sek Chuen

AU - Akowuah, Gabriel Akyirem

AU - Lee, Siew Keah

AU - Mai, Chun Wai

AU - Chew, Yik Ling

N1 - Funding Information: The authors would like to acknowledge the support of the Fundamental Research Grant Scheme (FRGS) (FRGS/1/2021/STG02/UCSI/02/1) from the Ministry of Higher Education Malaysia and UCSI University Research Excellence & Innovation Grant (REIG) (REIG-FPS-2023/037). Publisher Copyright: © 2024 by the authors.

PY - 2024/6

Y1 - 2024/6

N2 - Cassia alata, a traditional herb with a global presence, is renowned for its anti-inflammatory, antibacterial, and antifungal properties, making it a go-to remedy for skin ailments. While it has demonstrated wound healing capabilities in both in vitro and in vivo studies, the precise mechanisms remain elusive. This review aims to highlight its key phytochemicals, their effects, and the mechanism of action. The compounds that have been reviewed and discussed include kaempferol, apigenin, quercetin, rhein, and rutin. These polyphenols play important roles in normal and impaired wound healing processes, encompassing hemostasis, inflammation, proliferation, and tissue remodeling.

AB - Cassia alata, a traditional herb with a global presence, is renowned for its anti-inflammatory, antibacterial, and antifungal properties, making it a go-to remedy for skin ailments. While it has demonstrated wound healing capabilities in both in vitro and in vivo studies, the precise mechanisms remain elusive. This review aims to highlight its key phytochemicals, their effects, and the mechanism of action. The compounds that have been reviewed and discussed include kaempferol, apigenin, quercetin, rhein, and rutin. These polyphenols play important roles in normal and impaired wound healing processes, encompassing hemostasis, inflammation, proliferation, and tissue remodeling.

KW - antimicrobial

KW - antioxidant

KW - apigenin

KW - Cassia alata

KW - inflammation

KW - kaempferol

KW - quercetin

KW - rhein

KW - rutin

KW - wound healing

UR - https://www.scopus.com/pages/publications/85197123378

U2 - 10.3390/sci6020034

DO - 10.3390/sci6020034

M3 - Review Article

AN - SCOPUS:85197123378

SN - 2413-4155

VL - 6

JO - Sci

JF - Sci

IS - 2

M1 - 34

ER -

Cassia alata and Its Phytochemicals: A Promising Natural Strategy in Wound Recovery

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Keywords

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