Abstract
Enzymes of the cytochrome P450 superfamily can catalyse many types of oxidative transformations of a diverse substrate range. This review summarises recent work on an subset of P450s that accept their substrates in carrier protein-bound form. These examples show how the oxidative power and precision that P450s bring to natural products biosynthesis can be coupled with the advantages of using a carrier protein as a scaffold for oxidation.
Original language | English |
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Pages (from-to) | 323 - 326 |
Number of pages | 4 |
Journal | Metallomics |
Volume | 3 |
Issue number | 4 |
DOIs | |
Publication status | Published - 2011 |
Externally published | Yes |