Carrier protein substrates in cytochrome P450-catalysed oxidation

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Enzymes of the cytochrome P450 superfamily can catalyse many types of oxidative transformations of a diverse substrate range. This review summarises recent work on an subset of P450s that accept their substrates in carrier protein-bound form. These examples show how the oxidative power and precision that P450s bring to natural products biosynthesis can be coupled with the advantages of using a carrier protein as a scaffold for oxidation.
Original languageEnglish
Pages (from-to)323 - 326
Number of pages4
Issue number4
Publication statusPublished - 2011
Externally publishedYes

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