Carnosine and the processes of ageing

Alan R. Hipkiss, Estifanos Baye, Barbora de Courten

Research output: Contribution to journalReview ArticleOtherpeer-review

23 Citations (Scopus)

Abstract

The causes of ageing are usually regarded as multifactorial; thus effective regulation might be achieved by intervention at multiple sites. It has been suggested that the endogenous dipeptide carnosine, also available as a food supplement, possesses anti-ageing activity and may achieve its reported age-alleviating effects via a number of mechanisms. Carnosine's possible anti-ageing mechanisms are therefore discussed; the evidence suggests that inhibition of the mechanistic target of rapamycin and carbonyl scavenging may be involved.

Original languageEnglish
Pages (from-to)28-33
Number of pages6
JournalMaturitas
Volume93
DOIs
Publication statusPublished - 1 Nov 2016

Keywords

  • Advanced glycation end products
  • Ageing
  • Carnosine
  • Inflammation
  • Oxidative stress
  • Signalling pathways

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