Cardiovascular risk factors associated with lower baseline cognitive performance in HIV-positive persons

Edwina Wright, B Grund, K Robertson, Bruce Brew, Mollie Roediger, M Bain, F Drummond, M Vjecha, Jennifer Hoy, C Miller, A C Penalva de Oliveira, W Pumpradit, J Shlay, W El-Sadr, R Price

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128 Citations (Scopus)

Abstract

OBJECTIVE: To determine factors associated with baseline neurocognitive performance in HIV-infected participants enrolled in the Strategies for Management of Antiretroviral Therapy (SMART) neurology substudy. METHODS: Participants from Australia, North America, Brazil, and Thailand were administered a 5-test neurocognitive battery. Z scores and the neurocognitive performance outcome measure, the quantitative neurocognitive performance z score (QNPZ-5), were calculated using US norms. Neurocognitive impairment was defined as z scores
Original languageEnglish
Pages (from-to)864 - 873
Number of pages10
JournalNeurology
Volume75
Issue number7
Publication statusPublished - 2010

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