TY - JOUR
T1 - Cardiovascular medication use following percutaneous coronary intervention: the Australian experience
AU - Cole, Justin
AU - Brennan, Angela Leone
AU - Ajani, Andrew Edward
AU - Yan, Bryan P
AU - Duffy, Stephen
AU - Loane, Philippa Rose
AU - Reid, Christopher Michael
AU - Yudi, Matias B
AU - New, Gishel
AU - Black, Alexander John Roberts
AU - Shaw, James
AU - Clarke, David John
AU - Andrianopoulos, Nick
PY - 2014
Y1 - 2014
N2 - Aims: Despite the guidelines, a treatment gap exists in the delivery of pharmacotherapy for secondary prevention. We aimed to analyze the trend in guideline-based medication usage following percutaneous coronary intervention (PCI) using the Melbourne Interventional Group (MIG) registry over a 6-year period (2005-2010). Methods: The MIG registry prospectively collects demographical, clinical, and procedural characteristics of consecutive patients undergoing PCI. We assessed medication use (aspirin, clopidogrel, ACE inhibitors, angiotensin receptor blockers, beta-blockers, and lipid-lowering agents) at 30 days and 12 months in patients alive and able to provide the information. Results: The cohort consists of 12,813 patients who underwent 14,787 consecutive interventional procedures. They comprised 76 males: 22 were elderly (=75 years), 23 had diabetes, 2 had severe renal impairment, 2 had severe left ventricular dysfunction, 26 presented with STEMI, and 44 of patients received drug-eluting stent. Follow-up was complete for 97.8 of the cohort at 30 days (2.2 mortality) and 89.1 at 12 months (4 mortality). From 2005 to 2010, the percentage of patients taking all five classes of medications increased each year. In 2010 at 30 days, nearly 60 of patients took all five classes of medications, and by 12 months, 75 of patients were taking four or five classes of medications. Conclusion: In conclusion, while the increasing use of cardiovascular medicines in an at-risk Australian cohort is encouraging, a treatment gap appears to still exist.
AB - Aims: Despite the guidelines, a treatment gap exists in the delivery of pharmacotherapy for secondary prevention. We aimed to analyze the trend in guideline-based medication usage following percutaneous coronary intervention (PCI) using the Melbourne Interventional Group (MIG) registry over a 6-year period (2005-2010). Methods: The MIG registry prospectively collects demographical, clinical, and procedural characteristics of consecutive patients undergoing PCI. We assessed medication use (aspirin, clopidogrel, ACE inhibitors, angiotensin receptor blockers, beta-blockers, and lipid-lowering agents) at 30 days and 12 months in patients alive and able to provide the information. Results: The cohort consists of 12,813 patients who underwent 14,787 consecutive interventional procedures. They comprised 76 males: 22 were elderly (=75 years), 23 had diabetes, 2 had severe renal impairment, 2 had severe left ventricular dysfunction, 26 presented with STEMI, and 44 of patients received drug-eluting stent. Follow-up was complete for 97.8 of the cohort at 30 days (2.2 mortality) and 89.1 at 12 months (4 mortality). From 2005 to 2010, the percentage of patients taking all five classes of medications increased each year. In 2010 at 30 days, nearly 60 of patients took all five classes of medications, and by 12 months, 75 of patients were taking four or five classes of medications. Conclusion: In conclusion, while the increasing use of cardiovascular medicines in an at-risk Australian cohort is encouraging, a treatment gap appears to still exist.
UR - http://onlinelibrary.wiley.com/doi/10.1111/1755-5922.12060/pdf
U2 - 10.1111/1755-5922.12060
DO - 10.1111/1755-5922.12060
M3 - Article
VL - 32
SP - 47
EP - 51
JO - Cardiovascular Therapeutics
JF - Cardiovascular Therapeutics
SN - 1755-5914
IS - 2
ER -