Cardiorenal syndromes: An Executive Summary from the Consensus Conference of the Acute Dialysis Quality Initiative (ADQI)

Claudio Ronco, Peter McCullough, Stefan D Anker, Inder Anand, Nadia Aspromonte, Sean M Bagshaw, Rinaldo Bellomo, Tomas Berl, Ilona Bobek, Dinna N Cruz, Luciano Daliento, Andrew Davenport, Mikko Haapio, Hans Hillege, Andrew A House, Nevin Katz, Alan Maisel, Sunil Mankad, Pierluigi Zanco, Alexandre MebazaaAlbert Palazzuoli, Federico Ronco, Andrew D S Shaw, Geoff Sheinfeld, Sachin Soni, Giorgio Vescovo, Nereo Zamperetti, Piotr Ponikowski

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

95 Citations (Scopus)


The cardiorenal syndrome (CRS) is a disorder of the heart and kidneys whereby acute or chronic dysfunction in one organ may induce acute or chronic dysfunction of the other. The general definition has been expanded into five subtypes reflecting the primacy of organ dysfunction and the time-frame of the syndrome: CRS type 1 = acute worsening of heart function leading to kidney injury and/or dysfunction; CRS type 2 = chronic abnormalities in heart function leading to kidney injury or dysfunction; CRS type 3 = acute worsening of kidney function leading to heart injury and/or dysfunction; CRS type 4 = chronic kidney disease leading to heart injury, disease and/or dysfunction, and CRS type 5 = systemic conditions leading to simultaneous injury and/or dysfunction of heart and kidney. Different pathophysiological mechanisms are involved in the combined dysfunction of heart and kidney in these five types of the syndrome.
Original languageEnglish
Title of host publicationCardiorenal Syndromes in Critical Care
Place of PublicationSwitzerland
PublisherS Karger AG
Pages54 - 67
Number of pages14
Publication statusPublished - 2010
Externally publishedYes

Publication series

NameContributions To Nephrology
PublisherS Karger AG
ISSN (Print)0302-5144

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