TY - JOUR
T1 - Cardio-respiratory control during sleep in infancy
AU - Horne, Rosemary Sylvia Claire
PY - 2014
Y1 - 2014
N2 - During the first year of life and particularly the first 6 months autonomic control of the cardio-respiratory system is still undergoing maturation and infants are at risk of cardio-respiratory instability. These instabilities are most marked during sleep, which is important as infants spend the majority of each 24 hours in sleep. Sleep state has a marked effect on the cardio-respiratory system with instabilities being more common in active sleep compared to quiet sleep. Responses to hypoxia are also immature during infancy and may make young infants more vulnerable to cardio-respiratory instability. It has been proposed that an inability to respond appropriately to a life threatening event underpins the Sudden Infant Death Syndrome (SIDS). The major risk factors for SIDS, prone sleeping and maternal smoking, both impair cardio-respiratory control in normal healthy term infants.
AB - During the first year of life and particularly the first 6 months autonomic control of the cardio-respiratory system is still undergoing maturation and infants are at risk of cardio-respiratory instability. These instabilities are most marked during sleep, which is important as infants spend the majority of each 24 hours in sleep. Sleep state has a marked effect on the cardio-respiratory system with instabilities being more common in active sleep compared to quiet sleep. Responses to hypoxia are also immature during infancy and may make young infants more vulnerable to cardio-respiratory instability. It has been proposed that an inability to respond appropriately to a life threatening event underpins the Sudden Infant Death Syndrome (SIDS). The major risk factors for SIDS, prone sleeping and maternal smoking, both impair cardio-respiratory control in normal healthy term infants.
UR - http://www.sciencedirect.com/science/article/pii/S1526054213000249
U2 - 10.1016/j.prrv.2013.02.012
DO - 10.1016/j.prrv.2013.02.012
M3 - Article
SN - 1526-0542
VL - 15
SP - 163
EP - 169
JO - Paediatric Respiratory Reviews
JF - Paediatric Respiratory Reviews
IS - 2
ER -