Microvascular obstruction (MVO) is a strong independent predictor of left ventricular remodelling and mortality following ST-segment elevation myocardial infarction (STEMI). Microvascular obstruction can be identified at angiography or with gadolinium-enhanced cardiac MRI (CMR). First-pass perfusion CMR also allows a novel quantitative evaluation of myocardial blood flow (MBF) that might provide superior predictive data in the assessment of MVO. We sought to compare angiographic and CMR derived methodologies in the assessment of MVO to determine the optimal methodology that best predicts the surrogate outcome marker of left ventricular function post STEMI.
Wong, D., Leung, M. C. W., Richardson, J. D., Puri, R., Bertaso, A., Williams, K., Meredith, I. T., Teo, K. S. L., Worthley, M. I., & Worthley, S. G. (2012). Cardiac magnetic resonance derived late microvascular obstruction assessment post ST-segment elevation myocardial infarction is the best predictor of left ventricular function: a comparison of angiographic and cardiac magnetic resonance derived measu. International Journal of Cardiovascular Imaging, 28(8), 1971 - 1981. https://doi.org/10.1007/s10554-012-0021-9