Cardiac alternans suppression under T ± ε feedback control: nonlinear dynamics analysis

Shiuan Ni Liang; Duy Manh Le; Pik Yin Lai

doi:10.1142/S0218127419300362

Cardiac alternans suppression under T ± ε feedback control: nonlinear dynamics analysis

Shiuan Ni Liang, Duy Manh Le, Pik Yin Lai

Malaysia Sch of Engineering

Research output: Contribution to journal › Article › Research › peer-review

Abstract

The nonlinear dynamical properties of the recently proposed T ± feedback control for suppressing cardiac alternans is investigated in detail for the discrete cardiac restitution map model and the continuous Luo-Rudy I ionic model. It is shown that cardiac alternans, induced by fast pacing, can be dramatically reduced by small changes of fixed magnitude () under feedback control when exceeds a critical threshold. Remarkably, the suppression is achieved by utilizing the induced chaotic dynamics. Detailed information on the nature and mechanism of the control, and properties of the attractors are analyzed and discussed in the light of nonlinear dynamics.

Original language	English
Article number	1930036
Number of pages	15
Journal	International Journal of Bifurcation and Chaos in Applied Sciences and Engineering
Volume	29
Issue number	13
DOIs	https://doi.org/10.1142/S0218127419300362
Publication status	Published - 15 Dec 2019

Keywords

application of chaos
cardiac dynamics
feedback control
Nonlinear dynamics and chaos

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10.1142/S0218127419300362

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title = "Cardiac alternans suppression under T ± ε feedback control: nonlinear dynamics analysis",

abstract = "The nonlinear dynamical properties of the recently proposed T ± feedback control for suppressing cardiac alternans is investigated in detail for the discrete cardiac restitution map model and the continuous Luo-Rudy I ionic model. It is shown that cardiac alternans, induced by fast pacing, can be dramatically reduced by small changes of fixed magnitude () under feedback control when exceeds a critical threshold. Remarkably, the suppression is achieved by utilizing the induced chaotic dynamics. Detailed information on the nature and mechanism of the control, and properties of the attractors are analyzed and discussed in the light of nonlinear dynamics.",

keywords = "application of chaos, cardiac dynamics, feedback control, Nonlinear dynamics and chaos",

author = "Liang, {Shiuan Ni} and Le, {Duy Manh} and Lai, {Pik Yin}",

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T2 - nonlinear dynamics analysis

AU - Liang, Shiuan Ni

AU - Le, Duy Manh

AU - Lai, Pik Yin

N1 - Funding Information: This work has been supported by the Ministry of Science and Technology of ROC under the grant no. MoST 107-2112-M-008-013-MY3, and NCTS of Taiwan. Publisher Copyright: © 2019 World Scientific Publishing Company. Copyright: Copyright 2019 Elsevier B.V., All rights reserved.

PY - 2019/12/15

Y1 - 2019/12/15

N2 - The nonlinear dynamical properties of the recently proposed T ± feedback control for suppressing cardiac alternans is investigated in detail for the discrete cardiac restitution map model and the continuous Luo-Rudy I ionic model. It is shown that cardiac alternans, induced by fast pacing, can be dramatically reduced by small changes of fixed magnitude () under feedback control when exceeds a critical threshold. Remarkably, the suppression is achieved by utilizing the induced chaotic dynamics. Detailed information on the nature and mechanism of the control, and properties of the attractors are analyzed and discussed in the light of nonlinear dynamics.

AB - The nonlinear dynamical properties of the recently proposed T ± feedback control for suppressing cardiac alternans is investigated in detail for the discrete cardiac restitution map model and the continuous Luo-Rudy I ionic model. It is shown that cardiac alternans, induced by fast pacing, can be dramatically reduced by small changes of fixed magnitude () under feedback control when exceeds a critical threshold. Remarkably, the suppression is achieved by utilizing the induced chaotic dynamics. Detailed information on the nature and mechanism of the control, and properties of the attractors are analyzed and discussed in the light of nonlinear dynamics.

KW - application of chaos

KW - cardiac dynamics

KW - feedback control

KW - Nonlinear dynamics and chaos

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M1 - 1930036

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Cardiac alternans suppression under T ± ε feedback control: nonlinear dynamics analysis

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