Carbohydrate-based scaffolds in drug discovery

Bernd Becker, Glenn C. Condie, Giang Thanh Le, Wim Meutermans

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)


Carbohydrates have been proven as valuable scaffolds to display pharmocophores and the resulting molecules have demonstrated useful biological activity towards various targets including the somatostatin receptors (SSTR), integrins, HIV-1 protease, matrix metalloproteinases (MMP), multidrug resistance-associated protein (MRP), and as RNA binders. Carbohydrate-based compounds have also shown antibacterial and herbicidal activity.

Original languageEnglish
Pages (from-to)1299-1309
Number of pages11
JournalMini-Reviews in Medicinal Chemistry
Issue number12
Publication statusPublished - 1 Dec 2006
Externally publishedYes


  • Carbohydrate scaffolds
  • Carbohydrates
  • Combinatorial chemistry
  • Mimetics

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