Capillary gas chromatography and gas chromatography-mass spectrometry of silicon(IV) derivatives of porphyrins with polar substituents

Philip J. Marriott, Geoffrey Eglinton

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The successful gas chromatography (GC) of a number of standard polar porphyrins (with ester side chains) is reported for the first time. This is effected by preparation of their bis(trimethylsiloxy)silicon(IV) derivatives which show considerably greater volatility than the free base porphyrin precursor. Results for the mass spectrometric (MS) analysis (as GC-MS) are presented, thus facilitating identification of some of the components which almost coelute, and establishing the presence of a homologue (presumably a mixed ester) of one of the porphyrins. The GC retention volumes are correlated with structural features of the compounds, and this enables a superficial prediction of anticipated retention indices for other biologically significant polar porphyrins.

Original languageEnglish
Pages (from-to)311-321
Number of pages11
JournalJournal of Chromatography A
Issue number2
Publication statusPublished - 19 Nov 1982
Externally publishedYes

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