Cannula design

Shaun David Gregory, Jay Zwischenberger, Dongfang Wang, Sam Liao, Mark Slaughter

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

1 Citation (Scopus)


The anatomical interaction between mechanical circulatory or respiratory support and the patient is achieved by specially designed tubes called cannulae. Despite advancements in cannula design for ventricular assist devices (VADs), extracorporeal membrane oxygenation (ECMO), and total artificial hearts (TAH), cannula-related complications such as bleeding and thrombus formation remain prevalent. There is no gold standard cannula design, with almost all clinically used devices incorporating a unique cannula design or placement. Inflow (flow from patient to device) and outflow (flow from device to patient) cannula design has focused on methods to deliver sufficient cardiac output, improve vessel flow dynamics, reduce postoperative bleeding, and other anatomical considerations. However, continued development of VAD, ECMO, and TAH cannula design is required to reduce postoperative complications and improve patient outcomes.

Original languageEnglish
Title of host publicationMechanical Circulatory and Respiratory Support
EditorsShaun D. Gregory, Michael C. Stevens, John F. Fraser
Place of PublicationLondon UK
PublisherAcademic Press
Number of pages30
ISBN (Electronic)9780128104927
ISBN (Print)9780128104910
Publication statusPublished - 13 Oct 2017
Externally publishedYes


  • Cannula
  • Cuff
  • Extracorporeal membrane oxygenation
  • Graft
  • Total artificial heart
  • Ventricular assist device

Cite this