Cancer-related cognitive impairment in patients with non-central nervous system malignancies: an overview for oncology providers from the MASCC Neurological Complications Study Group

Samantha J. Mayo, Maryam Lustberg, Haryana M. Dhillon, Zev M. Nakamura, Deborah H. Allen, Diane Von Ah, Michelle C. Janelsins, Alexandre Chan, Karin Olson, Chia Jie Tan, Yi Long Toh, Jeong Oh, Lisa Grech, Yin Ting Cheung, Ishwaria Mohan Subbiah, Duska Petranovic, James D'Olimpio, Margherita Gobbo, Susanne Koeppen, Charles L. LoprinziLinda Pang, Shivani Shinde, Olanipekun Ntukidem, Katherine B. Peters

Research output: Contribution to journalReview ArticleResearchpeer-review

9 Citations (Scopus)


Cancer-related cognitive impairment (CRCI) is commonly experienced by individuals with non-central nervous system cancers throughout the disease and treatment trajectory. CRCI can have a substantial impact on the functional ability and quality of life of patients and their families. To mitigate the impact, oncology providers must know how to identify, assess, and educate patients and caregivers. The objective of this review is to provide oncology clinicians with an overview of CRCI in the context of adults with non-central nervous system cancers, with a particular focus on current approaches in its identification, assessment, and management.

Original languageEnglish
Pages (from-to)2821–2840
Number of pages20
JournalSupportive Care in Cancer
Issue number6
Publication statusPublished - Jun 2021


  • Cancer
  • Cancer-related cognitive impairment
  • Chemotherapy-related cognitive impairment
  • Cognition
  • Cognitive functioning
  • CRCI

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