TY - JOUR
T1 - Cancer incidence and mortality in Asian countries
T2 - a trend analysis
AU - Huang, Junjie
AU - Ngai, Chun Ho
AU - Deng, Yunyang
AU - Tin, Man Sing
AU - Lok, Veeleah
AU - Zhang, Lin
AU - Yuan, Jinqiu
AU - Xu, Wanghong
AU - Zheng, Zhi-Jie
AU - Wong, Martin C.S.
N1 - Funding Information:
We acknowledged the assistance from Mr Wing Chung Chan, JC School of Public Health and Primary Care, The Chinese University of Hong Kong, in the journal submission. The author(s) received no financial support for the research, authorship, and/or publication of this article.
Publisher Copyright:
© The Author(s) 2022.
PY - 2022
Y1 - 2022
N2 - Background: This study aimed to evaluate the updated burden and temporal trends of cancer incidence and mortality in Asian countries. Methodology: The data used in this study were retrieved from the Global Cancer Observatory, Cancer Incidence in Five Continents volumes I-XI, and the World Health Organization mortality database. These data were used to calculate the Average Annual Percentage Change (AAPC), with a 95% confidence interval (CI) by joinpoint regression analysis to determine the epidemiological trend in the past decade. Results: In 2020, the cancer incidence in Asia was 169.1 per 1 00 000, accounting for 49.3% of the global cancer incidence. The most common cancers included lung (13.8%), breast (10.8%) and colorectal (10.6%) cancers. Its mortality was 101.6 per 1 00 000 (58.3% of the global cancer death) with lung (19.2%), liver (10.5%) and stomach (9.9%) cancers being the most common causes of cancer death. The cancer incidence had been increasing in female population, with Korea (AAPC = 5.73, 95% CI [5.30, 6.17], P <.001), Japan (AAPC = 2.67, 95% CI [2.12, 3.23], P <.001) and Kuwait (AAPC = 2.08, 95% CI [.49, 3.69], P =.016) showing the most significant increases in the past decade. The incidence increase was also observed among population aged <40 years old, with Korea (female AAPC = 8.42, 95% CI [7.40, 9.45], P <.001; male AAPC = 5.28, 95% CI [4.23, 6.33], P <.001), China (female AAPC = 2.94, 95% CI [2.07, 3.81], P <.001; male AAPC = 1.37, 95% CI [.57, 2.18], P =.004) and Japan (female AAPC = 2.88, 95% CI [1.88, 3.88], P =.016; male AAPC = 1.59, 95% CI [.40, 2.78], P =.015) showing the most significant increases. However, there was an overall decreasing trend of cancer mortality. Conclusions: There was a substantial burden of cancer incidence and mortality in Asia. Although there was a decreasing trend in cancer mortality, its incidence had been increasing especially among female and younger populations. Future studies could be done to further investigate the potential reasons for these epidemiologic trends.
AB - Background: This study aimed to evaluate the updated burden and temporal trends of cancer incidence and mortality in Asian countries. Methodology: The data used in this study were retrieved from the Global Cancer Observatory, Cancer Incidence in Five Continents volumes I-XI, and the World Health Organization mortality database. These data were used to calculate the Average Annual Percentage Change (AAPC), with a 95% confidence interval (CI) by joinpoint regression analysis to determine the epidemiological trend in the past decade. Results: In 2020, the cancer incidence in Asia was 169.1 per 1 00 000, accounting for 49.3% of the global cancer incidence. The most common cancers included lung (13.8%), breast (10.8%) and colorectal (10.6%) cancers. Its mortality was 101.6 per 1 00 000 (58.3% of the global cancer death) with lung (19.2%), liver (10.5%) and stomach (9.9%) cancers being the most common causes of cancer death. The cancer incidence had been increasing in female population, with Korea (AAPC = 5.73, 95% CI [5.30, 6.17], P <.001), Japan (AAPC = 2.67, 95% CI [2.12, 3.23], P <.001) and Kuwait (AAPC = 2.08, 95% CI [.49, 3.69], P =.016) showing the most significant increases in the past decade. The incidence increase was also observed among population aged <40 years old, with Korea (female AAPC = 8.42, 95% CI [7.40, 9.45], P <.001; male AAPC = 5.28, 95% CI [4.23, 6.33], P <.001), China (female AAPC = 2.94, 95% CI [2.07, 3.81], P <.001; male AAPC = 1.37, 95% CI [.57, 2.18], P =.004) and Japan (female AAPC = 2.88, 95% CI [1.88, 3.88], P =.016; male AAPC = 1.59, 95% CI [.40, 2.78], P =.015) showing the most significant increases. However, there was an overall decreasing trend of cancer mortality. Conclusions: There was a substantial burden of cancer incidence and mortality in Asia. Although there was a decreasing trend in cancer mortality, its incidence had been increasing especially among female and younger populations. Future studies could be done to further investigate the potential reasons for these epidemiologic trends.
KW - Cancer
KW - Asian
KW - incidence
KW - mortality
KW - disease burden
KW - trend analysis
KW - epidemiology
KW - Average Annual Percentage Change
UR - http://www.scopus.com/inward/record.url?scp=85133146107&partnerID=8YFLogxK
U2 - 10.1177/10732748221095955
DO - 10.1177/10732748221095955
M3 - Article
C2 - 35770775
AN - SCOPUS:85133146107
SN - 1073-2748
VL - 29
JO - Cancer Control
JF - Cancer Control
ER -
