Can you reduce your AGE?. Strategies to prevent AGE accumulation in diabetes

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Abstract

Advanced glycation end-products (AGEs) contribute to the development and progression of diabetic kidney disease. Several different strategies have been developed to prevent the accumulation of AGEs in experimental diabetes, many of which have proved highly effective in attenuating renal damage in experimental models, even the absence of blood glucose control. These data suggests that if AGEs can be directly treated, some of the complications of diabetes may also be prevented.

Original languageEnglish
Pages (from-to)85-92
Number of pages8
JournalDrug Discovery Today: Therapeutic Strategies
Volume4
Issue number1
DOIs
Publication statusPublished - 21 Dec 2007
Externally publishedYes

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