Can pre-hospital administration reduce time to initial antibiotic therapy in septic patients?

Daniel Cudini, Karen Smith, Stephen Bernard, Michael Stephenson, Emily Andrew, Peter Cameron, Mark Lum, Andrew Udy, on behalf of the ARISE Investigators

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Abstract

Objective: To quantify the potential time saved with pre-hospital antibiotic therapy in sepsis. Methods: Study data for adult patients transported by Ambulance Victoria (AV), and enrolled into the Australasian Resuscitation In Sepsis Evaluation (ARISE), were linked with pre-hospital electronic records. Results: An AV record was identified for 240 of 341 ARISE patients. The pre-hospital case notes referred to potential infection in 165 patients. The median time to first antibiotic administration from loading the patient into the ambulance was 107 (74–160) min. Conclusions: ARISE patients in Victoria were frequently identified pre-hospital. An opportunity exists to study the feasibility of pre-hospital antibiotic therapy.

Original languageEnglish
Pages (from-to)669-672
Number of pages4
JournalEMA - Emergency Medicine Australasia
Volume31
Issue number4
DOIs
Publication statusPublished - Aug 2019

Keywords

  • antibiotics
  • out of hospital
  • pre-hospital
  • sepsis
  • sepsis management

Cite this

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title = "Can pre-hospital administration reduce time to initial antibiotic therapy in septic patients?",
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Can pre-hospital administration reduce time to initial antibiotic therapy in septic patients? / Cudini, Daniel; Smith, Karen; Bernard, Stephen; Stephenson, Michael; Andrew, Emily; Cameron, Peter; Lum, Mark; Udy, Andrew; on behalf of the ARISE Investigators.

In: EMA - Emergency Medicine Australasia, Vol. 31, No. 4, 08.2019, p. 669-672.

Research output: Contribution to journalArticleResearchpeer-review

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T1 - Can pre-hospital administration reduce time to initial antibiotic therapy in septic patients?

AU - Cudini, Daniel

AU - Smith, Karen

AU - Bernard, Stephen

AU - Stephenson, Michael

AU - Andrew, Emily

AU - Cameron, Peter

AU - Lum, Mark

AU - Udy, Andrew

AU - on behalf of the ARISE Investigators

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AB - Objective: To quantify the potential time saved with pre-hospital antibiotic therapy in sepsis. Methods: Study data for adult patients transported by Ambulance Victoria (AV), and enrolled into the Australasian Resuscitation In Sepsis Evaluation (ARISE), were linked with pre-hospital electronic records. Results: An AV record was identified for 240 of 341 ARISE patients. The pre-hospital case notes referred to potential infection in 165 patients. The median time to first antibiotic administration from loading the patient into the ambulance was 107 (74–160) min. Conclusions: ARISE patients in Victoria were frequently identified pre-hospital. An opportunity exists to study the feasibility of pre-hospital antibiotic therapy.

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