Abstract
Our current knowledge of NK-cell recognition and effector function suggests that it will be possible to design various new NK-cell-based immunotherapies against human cancer. The application of NK cells is already showing promise using HLA-mismatched haematopoietic stem cell transplantation for treatment of haematological malignancies. A better understanding of NK-cell heterogeneity and function will only broaden the applications for human cancer. Here we review the key developments that will propel this field.
| Original language | English |
|---|---|
| Pages (from-to) | 2964-2968 |
| Number of pages | 5 |
| Journal | European Journal of Immunology |
| Volume | 38 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - 1 Dec 2008 |
| Externally published | Yes |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Cancer
- Immunosurveillance
- NK cells
- Therapy
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