Calcitonin

Anna Ostrovskaya; David Findlay; Patrick Sexton; Sebastian Furness

doi:10.1016/B978-0-12-809324-5.03223-5

Calcitonin

Anna Ostrovskaya, David Findlay, Patrick Sexton, Sebastian Furness

Drug Discovery Biology

Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review

5 Citations (Scopus)

Abstract

Calcitonin (CT) is a peptide that is synthesized in the mammalian thyroid gland as well as the central nervous system, reproductive organs, liver, kidney, and elsewhere. Its receptor is found in many mammalian cell types and tissues, and CT is a potent inhibitor of osteoclast-mediated bone resorption. A rudimentary understanding of the chemistry and mechanisms of action of CT led to its use in treatment of various bone disorders, and further analysis of its diverse roles may lead to additional clinical applications.

Original language	English
Title of host publication	Reference Module in Neuroscience and Biobehavioral Psychology
Publisher	Elsevier
Number of pages	12
ISBN (Electronic)	9780128093245
DOIs	https://doi.org/10.1016/B978-0-12-809324-5.03223-5
Publication status	Published - 1 Jan 2016

Keywords

Adrenomedullin
Amylin
Calcitonin
Calcitonin gene-related peptide
Calcitonin receptor
Calcitonin-like receptor
Cancer
CTR
G protein-coupled receptor
Osteoclasts
Thyroid

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/B978-0-12-809324-5.03223-5

Cite this

@inbook{790e85776c674e83aa921345d438fe19,

title = "Calcitonin",

abstract = "Calcitonin (CT) is a peptide that is synthesized in the mammalian thyroid gland as well as the central nervous system, reproductive organs, liver, kidney, and elsewhere. Its receptor is found in many mammalian cell types and tissues, and CT is a potent inhibitor of osteoclast-mediated bone resorption. A rudimentary understanding of the chemistry and mechanisms of action of CT led to its use in treatment of various bone disorders, and further analysis of its diverse roles may lead to additional clinical applications.",

keywords = "Adrenomedullin, Amylin, Calcitonin, Calcitonin gene-related peptide, Calcitonin receptor, Calcitonin-like receptor, Cancer, CTR, G protein-coupled receptor, Osteoclasts, Thyroid",

author = "Anna Ostrovskaya and David Findlay and Patrick Sexton and Sebastian Furness",

year = "2016",

month = jan,

day = "1",

doi = "10.1016/B978-0-12-809324-5.03223-5",

language = "English",

booktitle = "Reference Module in Neuroscience and Biobehavioral Psychology",

publisher = "Elsevier",

address = "Netherlands",

}

TY - CHAP

T1 - Calcitonin

AU - Ostrovskaya, Anna

AU - Findlay, David

AU - Sexton, Patrick

AU - Furness, Sebastian

PY - 2016/1/1

Y1 - 2016/1/1

N2 - Calcitonin (CT) is a peptide that is synthesized in the mammalian thyroid gland as well as the central nervous system, reproductive organs, liver, kidney, and elsewhere. Its receptor is found in many mammalian cell types and tissues, and CT is a potent inhibitor of osteoclast-mediated bone resorption. A rudimentary understanding of the chemistry and mechanisms of action of CT led to its use in treatment of various bone disorders, and further analysis of its diverse roles may lead to additional clinical applications.

AB - Calcitonin (CT) is a peptide that is synthesized in the mammalian thyroid gland as well as the central nervous system, reproductive organs, liver, kidney, and elsewhere. Its receptor is found in many mammalian cell types and tissues, and CT is a potent inhibitor of osteoclast-mediated bone resorption. A rudimentary understanding of the chemistry and mechanisms of action of CT led to its use in treatment of various bone disorders, and further analysis of its diverse roles may lead to additional clinical applications.

KW - Adrenomedullin

KW - Amylin

KW - Calcitonin

KW - Calcitonin gene-related peptide

KW - Calcitonin receptor

KW - Calcitonin-like receptor

KW - Cancer

KW - CTR

KW - G protein-coupled receptor

KW - Osteoclasts

KW - Thyroid

UR - http://www.scopus.com/inward/record.url?scp=85076831522&partnerID=8YFLogxK

U2 - 10.1016/B978-0-12-809324-5.03223-5

DO - 10.1016/B978-0-12-809324-5.03223-5

M3 - Chapter (Book)

BT - Reference Module in Neuroscience and Biobehavioral Psychology

PB - Elsevier

ER -

Calcitonin

Abstract

Keywords

UN SDGs

Access to Document

Other files and links

Cite this