Calcitonin

Anna Ostrovskaya, David Findlay, Patrick Sexton, Sebastian Furness

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

3 Citations (Scopus)

Abstract

Calcitonin (CT) is a peptide that is synthesized in the mammalian thyroid gland as well as the central nervous system, reproductive organs, liver, kidney, and elsewhere. Its receptor is found in many mammalian cell types and tissues, and CT is a potent inhibitor of osteoclast-mediated bone resorption. A rudimentary understanding of the chemistry and mechanisms of action of CT led to its use in treatment of various bone disorders, and further analysis of its diverse roles may lead to additional clinical applications.

Original languageEnglish
Title of host publicationReference Module in Neuroscience and Biobehavioral Psychology
PublisherElsevier
Number of pages12
ISBN (Electronic)9780128093245
DOIs
Publication statusPublished - 1 Jan 2016

Keywords

  • Adrenomedullin
  • Amylin
  • Calcitonin
  • Calcitonin gene-related peptide
  • Calcitonin receptor
  • Calcitonin-like receptor
  • Cancer
  • CTR
  • G protein-coupled receptor
  • Osteoclasts
  • Thyroid

Cite this