TY - JOUR
T1 - C3d and C4d deposition early after lung transplantation
AU - Westall, Glen Philip
AU - Snell, Gregory I
AU - McLean, Catriona Ann
AU - Kotsimbos, Tom C
AU - Williams, Trevor John
AU - Magro, Cynthia
PY - 2008
Y1 - 2008
N2 - Complement staining as a predictor of antibody-mediated rejection (AMR) after lung transplantation continues to be debated. In a cohort of 33 lung transplant recipients (LTRs) we assessed early post-transplant (=3 months) graft deposition of the complement factors C3d and C4d and correlated staining with clinical outcome. A retrospective analysis of allograft C3d and C4d deposition was performed by an experienced histopathologist blinded to clinical outcomes. Biopsies were graded 0 to 3 based on extent of septal capillary complement staining
AB - Complement staining as a predictor of antibody-mediated rejection (AMR) after lung transplantation continues to be debated. In a cohort of 33 lung transplant recipients (LTRs) we assessed early post-transplant (=3 months) graft deposition of the complement factors C3d and C4d and correlated staining with clinical outcome. A retrospective analysis of allograft C3d and C4d deposition was performed by an experienced histopathologist blinded to clinical outcomes. Biopsies were graded 0 to 3 based on extent of septal capillary complement staining
UR - http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6VSG-4SN8V6F-3&_user=542840&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000027659&_ver5
U2 - 10.1016/j.healun.2008.03.018
DO - 10.1016/j.healun.2008.03.018
M3 - Article
SN - 1053-2498
VL - 27
SP - 722
EP - 728
JO - Journal of Heart and Lung Transplantation
JF - Journal of Heart and Lung Transplantation
IS - 7
ER -