c-Rel: shaping CD4 regulatory T cell development in unexpected ways

Steven Demetrious Gerondakis, Thomas Fulford, Raelene Joy Grumont

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)


In the thymus, sequential antigen and cytokine receptor signals direct the stepwise differentiation of multi-potential CD4+CD8+ thymic precursors into Foxp3+ CD4 regulatory T cells (Tregs). In this Point of View article we discuss our recent findings about how the c-Rel transcription factor orchestrates this developmental process.

Original languageEnglish
Pages (from-to)245 - 249
Number of pages5
JournalTranscription (Austin)
Issue number5
Publication statusPublished - Sep 2012

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