C-reactive protein levels in acute respiratory exacerbations of cystic fibrosis

Gayan Kathriachchige, Christopher Daley, Michael Pallin, Kevan Polkinghorne, Paul T. King

Research output: Contribution to journalArticleResearchpeer-review

Abstract

C-reactive protein (CRP) levels increase in response to bacterial infection and have been used to guide the use of antibiotics. We assessed CRP levels in a cohort of patients with cystic fibrosis (CF) admitted to hospital with an exacerbation of their lung disease, requiring treatment with broad-spectrum antibiotics. In this group, most subjects had CRP levels of less than 20 mg/L, including patients who had pneumonia. The clinical utility of the CRP in guiding antibiotic use in exacerbations of CF is limited.

Original languageEnglish
Pages (from-to)1392-1395
Number of pages4
JournalInternal Medicine Journal
Volume48
Issue number11
DOIs
Publication statusPublished - 1 Nov 2018

Keywords

  • antibiotic
  • C-reactive protein
  • exacerbation
  • pneumonia

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