Brushed polyethylene glycol and phosphorylcholine for grafting nanoparticles against protein binding

Bo Wang, Thomas Blin, Aleksandr Kakinen, Xinwei Ge, Emily H. Pilkington, John F. Quinn, Michael R. Whittaker, Thomas P. Davis, Pu Chun Ke, Feng Ding

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Abstract

To provide a molecular insight for guiding polymer coating in surface science and nanotechnology, here we examined the structures of brushed polyethylene glycol(bPEG)- and phosphorylcholine(bPC)-grafted iron oxide nanoparticles and analyzed their protein avoiding properties. We show bPC as an advantageous biomimetic alternative to PEG in rendering stealth nanostructures.

Original languageEnglish
Pages (from-to)6875-6879
Number of pages5
JournalPolymer Chemistry
Volume7
Issue number45
DOIs
Publication statusPublished - 7 Dec 2016

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