Bronchopulmonary dysplasia: Pathophysiology and potential anti-inflammatory therapies

Paris C. Papagianis, J. J. Pillow, Timothy J. Moss

Research output: Contribution to journalReview ArticleResearchpeer-review

Abstract

Inflammation of the preterm lungs is key to the pathogenesis of bronchopulmonary dysplasia (BPD), whether it arises as a consequence of intrauterine inflammation or postnatal respiratory management. This review explores steroidal and non-steroidal therapies for reducing neonatal pulmonary inflammation, aimed at treating or preventing BPD.

Original languageEnglish
Pages (from-to)34-41
Number of pages8
JournalPaediatric Respiratory Reviews
Volume30
DOIs
Publication statusPublished - 1 Apr 2019

Keywords

  • Bronchopulmonary dysplasia
  • Chorioamnionitis
  • Dexamethasone
  • Glucocorticoid
  • Inflammation
  • Pulmonary

Cite this

@article{9e7caf0a0b86418fb4fd4b3b9c30c8db,
title = "Bronchopulmonary dysplasia: Pathophysiology and potential anti-inflammatory therapies",
abstract = "Inflammation of the preterm lungs is key to the pathogenesis of bronchopulmonary dysplasia (BPD), whether it arises as a consequence of intrauterine inflammation or postnatal respiratory management. This review explores steroidal and non-steroidal therapies for reducing neonatal pulmonary inflammation, aimed at treating or preventing BPD.",
keywords = "Bronchopulmonary dysplasia, Chorioamnionitis, Dexamethasone, Glucocorticoid, Inflammation, Pulmonary",
author = "Papagianis, {Paris C.} and Pillow, {J. J.} and Moss, {Timothy J.}",
year = "2019",
month = "4",
day = "1",
doi = "10.1016/j.prrv.2018.07.007",
language = "English",
volume = "30",
pages = "34--41",
journal = "Paediatric Respiratory Reviews",
issn = "1526-0542",
publisher = "Elsevier",

}

Bronchopulmonary dysplasia : Pathophysiology and potential anti-inflammatory therapies. / Papagianis, Paris C.; Pillow, J. J.; Moss, Timothy J.

In: Paediatric Respiratory Reviews, Vol. 30, 01.04.2019, p. 34-41.

Research output: Contribution to journalReview ArticleResearchpeer-review

TY - JOUR

T1 - Bronchopulmonary dysplasia

T2 - Pathophysiology and potential anti-inflammatory therapies

AU - Papagianis, Paris C.

AU - Pillow, J. J.

AU - Moss, Timothy J.

PY - 2019/4/1

Y1 - 2019/4/1

N2 - Inflammation of the preterm lungs is key to the pathogenesis of bronchopulmonary dysplasia (BPD), whether it arises as a consequence of intrauterine inflammation or postnatal respiratory management. This review explores steroidal and non-steroidal therapies for reducing neonatal pulmonary inflammation, aimed at treating or preventing BPD.

AB - Inflammation of the preterm lungs is key to the pathogenesis of bronchopulmonary dysplasia (BPD), whether it arises as a consequence of intrauterine inflammation or postnatal respiratory management. This review explores steroidal and non-steroidal therapies for reducing neonatal pulmonary inflammation, aimed at treating or preventing BPD.

KW - Bronchopulmonary dysplasia

KW - Chorioamnionitis

KW - Dexamethasone

KW - Glucocorticoid

KW - Inflammation

KW - Pulmonary

UR - http://www.scopus.com/inward/record.url?scp=85052935106&partnerID=8YFLogxK

U2 - 10.1016/j.prrv.2018.07.007

DO - 10.1016/j.prrv.2018.07.007

M3 - Review Article

VL - 30

SP - 34

EP - 41

JO - Paediatric Respiratory Reviews

JF - Paediatric Respiratory Reviews

SN - 1526-0542

ER -