Abstract
Pulmonary hypertension (PH) complicating bronchopulmonary dysplasia (BPD) is known though echocardiographic (ECHO) criteria and clinical relevance are unclear. An audit of infants ≤ 28 weeks’ gestational age (GA) and with ‘severe’ BPD was carried out for the period January 2014 to May 2015. Six objective ECHO markers were decided a priori. During the period, 56 infants with GA and birthweight of 26 ± 1.4 weeks and 796 ± 190 g had ‘severe’ BPD. Twenty (35%) infants had no echocardiogram performed after 34 weeks’ corrected GA; the remaining 36 infants had an echocardiogram at 36.7 ± 2 weeks’ GA. ECHO parameters indicative of PH were noted in 22 (39.3%) infants in the overall cohort. The most common parameter was tricuspid regurgitation in 13/36 (36%) infants. The GA of infants with and without PH was comparable (25.8 ± 1.6 vs 25.8 ± 1.3 weeks, p = 0.9). The total duration of respiratory support in the BPD with PH group was significantly longer compared to those without (224 ± 130 vs 132 ± 82 days, p = 0.001). Overall, 29 (52%) infants were discharged on oxygen/respiratory support; the odds when PH was present were 2.2 (95% CI 0.8–5.7). This was not statistically significant. BPD associated PH contributes to respiratory sequelae. Objective ECHO criteria may aid ascertaining true incidence.
| Original language | English |
|---|---|
| Pages (from-to) | 39-43 |
| Number of pages | 5 |
| Journal | Progress in Pediatric Cardiology |
| Volume | 46 |
| DOIs | |
| Publication status | Published - 1 Sep 2017 |
Keywords
- Bronchopulmonary dysplasia
- Echocardiography
- Pulmonary hypertension
Cite this
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Bronchopulmonary dysplasia associated pulmonary hypertension : Making the best use of bedside echocardiography. / Revanna, Gopagondanahalli Krishna; Kunjunju, Ansar; Sehgal, Arvind.
In: Progress in Pediatric Cardiology, Vol. 46, 01.09.2017, p. 39-43.Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - Bronchopulmonary dysplasia associated pulmonary hypertension
T2 - Making the best use of bedside echocardiography
AU - Revanna, Gopagondanahalli Krishna
AU - Kunjunju, Ansar
AU - Sehgal, Arvind
PY - 2017/9/1
Y1 - 2017/9/1
N2 - Pulmonary hypertension (PH) complicating bronchopulmonary dysplasia (BPD) is known though echocardiographic (ECHO) criteria and clinical relevance are unclear. An audit of infants ≤ 28 weeks’ gestational age (GA) and with ‘severe’ BPD was carried out for the period January 2014 to May 2015. Six objective ECHO markers were decided a priori. During the period, 56 infants with GA and birthweight of 26 ± 1.4 weeks and 796 ± 190 g had ‘severe’ BPD. Twenty (35%) infants had no echocardiogram performed after 34 weeks’ corrected GA; the remaining 36 infants had an echocardiogram at 36.7 ± 2 weeks’ GA. ECHO parameters indicative of PH were noted in 22 (39.3%) infants in the overall cohort. The most common parameter was tricuspid regurgitation in 13/36 (36%) infants. The GA of infants with and without PH was comparable (25.8 ± 1.6 vs 25.8 ± 1.3 weeks, p = 0.9). The total duration of respiratory support in the BPD with PH group was significantly longer compared to those without (224 ± 130 vs 132 ± 82 days, p = 0.001). Overall, 29 (52%) infants were discharged on oxygen/respiratory support; the odds when PH was present were 2.2 (95% CI 0.8–5.7). This was not statistically significant. BPD associated PH contributes to respiratory sequelae. Objective ECHO criteria may aid ascertaining true incidence.
AB - Pulmonary hypertension (PH) complicating bronchopulmonary dysplasia (BPD) is known though echocardiographic (ECHO) criteria and clinical relevance are unclear. An audit of infants ≤ 28 weeks’ gestational age (GA) and with ‘severe’ BPD was carried out for the period January 2014 to May 2015. Six objective ECHO markers were decided a priori. During the period, 56 infants with GA and birthweight of 26 ± 1.4 weeks and 796 ± 190 g had ‘severe’ BPD. Twenty (35%) infants had no echocardiogram performed after 34 weeks’ corrected GA; the remaining 36 infants had an echocardiogram at 36.7 ± 2 weeks’ GA. ECHO parameters indicative of PH were noted in 22 (39.3%) infants in the overall cohort. The most common parameter was tricuspid regurgitation in 13/36 (36%) infants. The GA of infants with and without PH was comparable (25.8 ± 1.6 vs 25.8 ± 1.3 weeks, p = 0.9). The total duration of respiratory support in the BPD with PH group was significantly longer compared to those without (224 ± 130 vs 132 ± 82 days, p = 0.001). Overall, 29 (52%) infants were discharged on oxygen/respiratory support; the odds when PH was present were 2.2 (95% CI 0.8–5.7). This was not statistically significant. BPD associated PH contributes to respiratory sequelae. Objective ECHO criteria may aid ascertaining true incidence.
KW - Bronchopulmonary dysplasia
KW - Echocardiography
KW - Pulmonary hypertension
UR - http://www.scopus.com/inward/record.url?scp=85009343984&partnerID=8YFLogxK
U2 - 10.1016/j.ppedcard.2016.12.003
DO - 10.1016/j.ppedcard.2016.12.003
M3 - Article
VL - 46
SP - 39
EP - 43
JO - Progress in Pediatric Cardiology
JF - Progress in Pediatric Cardiology
SN - 1058-9813
ER -