Bradycardia and syncope as a presentation of cardiac allograft rejection involving the conducting system

Carrie S. Knight; José A. Tallaj; Barry K. Rayburn; Salpy V. Pamboukian; Robert Bourge; James K. Kirklin; David McGiffin; Silvio H. Litovsky

doi:10.1016/j.carpath.2008.10.006

Bradycardia and syncope as a presentation of cardiac allograft rejection involving the conducting system

Carrie S. Knight, José A. Tallaj, Barry K. Rayburn, Salpy V. Pamboukian, Robert Bourge, James K. Kirklin, David McGiffin, Silvio H. Litovsky

Research output: Contribution to journal › Article › Research › peer-review

17 Citations (Scopus)

Abstract

Post-heart transplantation bradycardic syncope and arrest could be due to preferential rejection of the conduction system. We present six heart transplant patients with this presentation, two of whom died. The autopsy of one of those patients demonstrated severe rejection of the conduction system, with only mild rejection throughout the rest of the myocardium. We postulate that aggressive therapy for rejection and pacemaker placement may result in improved survival in heart transplant recipients with this clinical presentation.

Original language	English
Pages (from-to)	117-120
Number of pages	4
Journal	Cardiovascular Pathology
Volume	19
Issue number	2
DOIs	https://doi.org/10.1016/j.carpath.2008.10.006
Publication status	Published - 1 Mar 2010
Externally published	Yes

Keywords

Bradycardia
Conducting system
Heart transplant
Rejection

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10.1016/j.carpath.2008.10.006

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abstract = "Post-heart transplantation bradycardic syncope and arrest could be due to preferential rejection of the conduction system. We present six heart transplant patients with this presentation, two of whom died. The autopsy of one of those patients demonstrated severe rejection of the conduction system, with only mild rejection throughout the rest of the myocardium. We postulate that aggressive therapy for rejection and pacemaker placement may result in improved survival in heart transplant recipients with this clinical presentation.",

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AU - Knight, Carrie S.

AU - Tallaj, José A.

AU - Rayburn, Barry K.

AU - Pamboukian, Salpy V.

AU - Bourge, Robert

AU - Kirklin, James K.

AU - McGiffin, David

AU - Litovsky, Silvio H.

PY - 2010/3/1

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AB - Post-heart transplantation bradycardic syncope and arrest could be due to preferential rejection of the conduction system. We present six heart transplant patients with this presentation, two of whom died. The autopsy of one of those patients demonstrated severe rejection of the conduction system, with only mild rejection throughout the rest of the myocardium. We postulate that aggressive therapy for rejection and pacemaker placement may result in improved survival in heart transplant recipients with this clinical presentation.

KW - Bradycardia

KW - Conducting system

KW - Heart transplant

KW - Rejection

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ER -

Bradycardia and syncope as a presentation of cardiac allograft rejection involving the conducting system

Abstract

Keywords

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