Abstract
A synthetic method to prepare oxazol-2(3H)-ones and 5-alkenyloxazolidin-2-ones efficiently that relies on a Brønsted acid-catalyzed cyclization of the respective secondary and tertiary β-amino-1,4-enols in ethanol is described. The reaction did not require the exclusion of air or moisture.
| Original language | English |
|---|---|
| Pages (from-to) | 1029-1032 |
| Number of pages | 4 |
| Journal | Asian Journal of Organic Chemistry |
| Volume | 8 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - Jul 2019 |
Keywords
- alcohols
- Brønsted acids
- cyclization
- heterocycles
- synthetic methods
Cite this
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Brønsted Acid-Catalyzed Cyclization of β-Amino-1,4-enols to Oxazol-2(3H)-ones and 5-Alkenyloxazolidin-2-ones. / Zhao, Yichao; Henry, Stuart Adam; Jin, Jianwen; Clarkson, Guy James; Chan, Philip Wai Hong.
In: Asian Journal of Organic Chemistry, Vol. 8, No. 7, 07.2019, p. 1029-1032.Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - Brønsted Acid-Catalyzed Cyclization of β-Amino-1,4-enols to Oxazol-2(3H)-ones and 5-Alkenyloxazolidin-2-ones
AU - Zhao, Yichao
AU - Henry, Stuart Adam
AU - Jin, Jianwen
AU - Clarkson, Guy James
AU - Chan, Philip Wai Hong
PY - 2019/7
Y1 - 2019/7
N2 - A synthetic method to prepare oxazol-2(3H)-ones and 5-alkenyloxazolidin-2-ones efficiently that relies on a Brønsted acid-catalyzed cyclization of the respective secondary and tertiary β-amino-1,4-enols in ethanol is described. The reaction did not require the exclusion of air or moisture.
AB - A synthetic method to prepare oxazol-2(3H)-ones and 5-alkenyloxazolidin-2-ones efficiently that relies on a Brønsted acid-catalyzed cyclization of the respective secondary and tertiary β-amino-1,4-enols in ethanol is described. The reaction did not require the exclusion of air or moisture.
KW - alcohols
KW - Brønsted acids
KW - cyclization
KW - heterocycles
KW - synthetic methods
UR - http://www.scopus.com/inward/record.url?scp=85066982076&partnerID=8YFLogxK
U2 - 10.1002/ajoc.201900277
DO - 10.1002/ajoc.201900277
M3 - Article
AN - SCOPUS:85066982076
VL - 8
SP - 1029
EP - 1032
JO - Asian Journal of Organic Chemistry
JF - Asian Journal of Organic Chemistry
SN - 2193-5807
IS - 7
ER -