TY - JOUR
T1 - Body composition and knee cartilage properties in healthy, community-based adults
AU - Wang, YuanYuan
AU - Wluka, Anita E
AU - English, Dallas R
AU - Teichtahl, Andrew
AU - Giles, Graham G
AU - O'Sullivan, Richard M
AU - Cicuttini, Flavia Maria
PY - 2007
Y1 - 2007
N2 - BACKGROUND: Although obesity is widely accepted as a risk factor for knee osteoarthritis, whether weight per se or the specific components of body composition are the major determinants of properties of articular knee cartilage is unclear. OBJECTIVE: To examine associations between anthropometric and body composition measures and knee cartilage properties in healthy adults. METHODS: 297 healthy adults with no clinical knee osteoarthritis were recruited from an existing community-based cohort. Anthropometric measures and body composition, including fat-free mass and fat mass assessed using bioelectrical impedance analysis, were measured at baseline (1990-4) and current follow-up (2003-4). Tibial cartilage volume and tibiofemoral cartilage defects were assessed using MRI at follow-up. RESULTS: After adjustment for potential confounders, baseline and current fat-free mass, independent of fat mass, were positively associated with tibial cartilage volume (all p
AB - BACKGROUND: Although obesity is widely accepted as a risk factor for knee osteoarthritis, whether weight per se or the specific components of body composition are the major determinants of properties of articular knee cartilage is unclear. OBJECTIVE: To examine associations between anthropometric and body composition measures and knee cartilage properties in healthy adults. METHODS: 297 healthy adults with no clinical knee osteoarthritis were recruited from an existing community-based cohort. Anthropometric measures and body composition, including fat-free mass and fat mass assessed using bioelectrical impedance analysis, were measured at baseline (1990-4) and current follow-up (2003-4). Tibial cartilage volume and tibiofemoral cartilage defects were assessed using MRI at follow-up. RESULTS: After adjustment for potential confounders, baseline and current fat-free mass, independent of fat mass, were positively associated with tibial cartilage volume (all p
UR - http://ard.bmj.com/cgi/reprint/66/9/1244
M3 - Article
SN - 0003-4967
VL - 66
SP - 1244
EP - 1248
JO - Annals of the Rheumatic Diseases
JF - Annals of the Rheumatic Diseases
IS - 9
ER -
