Body composition and knee cartilage properties in healthy, community-based adults

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Abstract

BACKGROUND: Although obesity is widely accepted as a risk factor for knee osteoarthritis, whether weight per se or the specific components of body composition are the major determinants of properties of articular knee cartilage is unclear. OBJECTIVE: To examine associations between anthropometric and body composition measures and knee cartilage properties in healthy adults. METHODS: 297 healthy adults with no clinical knee osteoarthritis were recruited from an existing community-based cohort. Anthropometric measures and body composition, including fat-free mass and fat mass assessed using bioelectrical impedance analysis, were measured at baseline (1990-4) and current follow-up (2003-4). Tibial cartilage volume and tibiofemoral cartilage defects were assessed using MRI at follow-up. RESULTS: After adjustment for potential confounders, baseline and current fat-free mass, independent of fat mass, were positively associated with tibial cartilage volume (all p
Original languageEnglish
Pages (from-to)1244 - 1248
Number of pages5
JournalAnnals of the Rheumatic Diseases
Volume66
Issue number9
Publication statusPublished - 2007

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