@article{c86ff835ac2a48e5bf8e9dad4c618c8f,
title = "Blood Pressure and Vascular Cognitive Impairment",
abstract = "High blood pressure (BP) is detrimental to brain health. High BP contributes to cognitive impairment and dementia through pathways independent of clinical stroke. Emerging evidence shows that the deleterious effect of high BP on cognition occurs across the life span, increasing the risk for early-onset and late-life dementia. The term vascular cognitive impairment includes cognitive disorders associated with cerebrovascular disease, regardless of the pathogenesis. This focused report is a narrative review that aims to summarize the epidemiology of BP and vascular cognitive impairment, including differences by sex, race, and ethnicity, as well as the management and reversibility of BP and vascular cognitive impairment. It also discusses knowledge gaps and future directions.",
keywords = "blood pressure, dementia, epidemiology, ethnicity, knowledge",
author = "Levine, {Deborah A.} and Springer, {Mellanie V.} and Amy Brodtmann",
note = "Funding Information: Dr Levine reports funding from the National Institute of Neurological Disorders and Stroke (NINDS) R01 NS102715 and National Institute of Aging (NIA) grants R01 AG051827 and RF1 AG068410 from the National Institutes of Health, Department of Health and Human Service. Dr Springer reports funding from the National Institute of Neurological Disorders and Stroke (NINDS) K01 NS11755 from the National Institutes of Health, Department of Health and Human Service. Dr Springer is also a site primary investigator for the DISCOVERY: Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on Recovery study (U19 NS115388). Dr Brodtmann sits on the editorial boards of Neurology and International Journal of Stroke and serves on a Biogen Australia Dementia Scientific Advisory Board. She is a current National Heart Foundation Future Fellow (104748) and reports prior or current funding from the National Health and Medical Research Council (NHMRC; GNT1171890, GNT1171816, GNT1158384, GNT1094974, GNT1045617, and GNT1020526) relevant to this article. Publisher Copyright: {\textcopyright} 2022 American Heart Association, Inc.",
year = "2022",
month = apr,
doi = "10.1161/STROKEAHA.121.036140",
language = "English",
volume = "53",
pages = "1104--1113",
journal = "Stroke",
issn = "0039-2499",
publisher = "American Heart Association",
number = "4",
}