Blood oxygenation changes resulting from suprathreshold transcranial magnetic stimulation

Richard Hilton Siddall Thomson, Jerome Joseph Maller, Zafiris Jeff Daskalakis, Paul Bernard Fitzgerald

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Abstract

The hemodynamic response to low-intensity transcranial magnetic stimulation (TMS) has previously been demonstrated at motor cortex using near infrared spectroscopy (NIRS). To investigate the effect of TMS on oxy-hemoglobin (HbO) at prefrontal cortex, both subthreshold and suprathreshold TMS relative to resting motor threshold (rMT) were applied at typical intensities used in experimental settings. Although there was no significant change after 90 and 110 rMT TMS, there was a significant drop in HbO after 130 rMT TMS. This drop was maximal at approximately 8 seconds post-TMS. This study may have implications for determining appropriate TMS intensities when stimulating nonmotor areas. ? 2011 Elsevier Inc. All rights reserved.
Original languageEnglish
Pages (from-to)165 - 168
Number of pages4
JournalBrain Stimulation
Volume4
Issue number3
DOIs
Publication statusPublished - 2011

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