Abstract
Purpose: The aim of the study was to test whether the mean of the highest and lowest glucose values on day 1 (Glu1) is a useful surrogate marker of mean blood glucose during the totality of intensive care unit (ICU) stay (Glutot). Materials and Methods: Glutot values were extracted from electronically stored biochemical databases (point-of-care laboratory) and Glu1 values from electronically stored prospectively collected patient databases in ICUs of 4 hospitals from January 2000 to October 2004. Statistical assessment of relationship between Glu1 and Glutot was done. Results: There were 197 227 blood glucose measurements for 8039 patients. The average of all blood glucose measurements was 8.22 ± 2.75 mmol/L. The difference between the average of all glucose values (N = 197 227) and average of Glu1 (n = 8039) was 0.17 mmol/L. This difference in each hospital was also small (0.26, -0.13, 0.12, and 0.37 mmol/L, respectively). Conclusions: Glu1 was a good predictor of Glutot across all study hospitals. This observation makes it possible to use Glu1 as a surrogate of glucose control during ICU stay and opens the door to understanding ICU glucose control across the whole of Australia and New Zealand.
| Original language | English |
|---|---|
| Pages (from-to) | 197-202 |
| Number of pages | 6 |
| Journal | Journal of Critical Care |
| Volume | 21 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 1 Jun 2006 |
| Externally published | Yes |
Keywords
- Blood glucose
- Glucose control
- Hyperglycemia
- Insulin
- Intensive care
Cite this
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Blood glucose on day of intensive care unit admission as a surrogate of subsequent glucose control in intensive care. / Egi, Moritoki; Bellomo, Rinaldo; Stachowski, Eddie; French, Craig J.; Hart, Graeme; Stow, Peter.
In: Journal of Critical Care, Vol. 21, No. 2, 01.06.2006, p. 197-202.Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - Blood glucose on day of intensive care unit admission as a surrogate of subsequent glucose control in intensive care
AU - Egi, Moritoki
AU - Bellomo, Rinaldo
AU - Stachowski, Eddie
AU - French, Craig J.
AU - Hart, Graeme
AU - Stow, Peter
PY - 2006/6/1
Y1 - 2006/6/1
N2 - Purpose: The aim of the study was to test whether the mean of the highest and lowest glucose values on day 1 (Glu1) is a useful surrogate marker of mean blood glucose during the totality of intensive care unit (ICU) stay (Glutot). Materials and Methods: Glutot values were extracted from electronically stored biochemical databases (point-of-care laboratory) and Glu1 values from electronically stored prospectively collected patient databases in ICUs of 4 hospitals from January 2000 to October 2004. Statistical assessment of relationship between Glu1 and Glutot was done. Results: There were 197 227 blood glucose measurements for 8039 patients. The average of all blood glucose measurements was 8.22 ± 2.75 mmol/L. The difference between the average of all glucose values (N = 197 227) and average of Glu1 (n = 8039) was 0.17 mmol/L. This difference in each hospital was also small (0.26, -0.13, 0.12, and 0.37 mmol/L, respectively). Conclusions: Glu1 was a good predictor of Glutot across all study hospitals. This observation makes it possible to use Glu1 as a surrogate of glucose control during ICU stay and opens the door to understanding ICU glucose control across the whole of Australia and New Zealand.
AB - Purpose: The aim of the study was to test whether the mean of the highest and lowest glucose values on day 1 (Glu1) is a useful surrogate marker of mean blood glucose during the totality of intensive care unit (ICU) stay (Glutot). Materials and Methods: Glutot values were extracted from electronically stored biochemical databases (point-of-care laboratory) and Glu1 values from electronically stored prospectively collected patient databases in ICUs of 4 hospitals from January 2000 to October 2004. Statistical assessment of relationship between Glu1 and Glutot was done. Results: There were 197 227 blood glucose measurements for 8039 patients. The average of all blood glucose measurements was 8.22 ± 2.75 mmol/L. The difference between the average of all glucose values (N = 197 227) and average of Glu1 (n = 8039) was 0.17 mmol/L. This difference in each hospital was also small (0.26, -0.13, 0.12, and 0.37 mmol/L, respectively). Conclusions: Glu1 was a good predictor of Glutot across all study hospitals. This observation makes it possible to use Glu1 as a surrogate of glucose control during ICU stay and opens the door to understanding ICU glucose control across the whole of Australia and New Zealand.
KW - Blood glucose
KW - Glucose control
KW - Hyperglycemia
KW - Insulin
KW - Intensive care
UR - http://www.scopus.com/inward/record.url?scp=33744905329&partnerID=8YFLogxK
U2 - 10.1016/j.jcrc.2006.03.003
DO - 10.1016/j.jcrc.2006.03.003
M3 - Article
VL - 21
SP - 197
EP - 202
JO - Journal of Critical Care
JF - Journal of Critical Care
SN - 0883-9441
IS - 2
ER -