Blood glucose on day of intensive care unit admission as a surrogate of subsequent glucose control in intensive care

Moritoki Egi, Rinaldo Bellomo, Eddie Stachowski, Craig J. French, Graeme Hart, Peter Stow

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Purpose: The aim of the study was to test whether the mean of the highest and lowest glucose values on day 1 (Glu1) is a useful surrogate marker of mean blood glucose during the totality of intensive care unit (ICU) stay (Glutot). Materials and Methods: Glutot values were extracted from electronically stored biochemical databases (point-of-care laboratory) and Glu1 values from electronically stored prospectively collected patient databases in ICUs of 4 hospitals from January 2000 to October 2004. Statistical assessment of relationship between Glu1 and Glutot was done. Results: There were 197 227 blood glucose measurements for 8039 patients. The average of all blood glucose measurements was 8.22 ± 2.75 mmol/L. The difference between the average of all glucose values (N = 197 227) and average of Glu1 (n = 8039) was 0.17 mmol/L. This difference in each hospital was also small (0.26, -0.13, 0.12, and 0.37 mmol/L, respectively). Conclusions: Glu1 was a good predictor of Glutot across all study hospitals. This observation makes it possible to use Glu1 as a surrogate of glucose control during ICU stay and opens the door to understanding ICU glucose control across the whole of Australia and New Zealand.

Original languageEnglish
Pages (from-to)197-202
Number of pages6
JournalJournal of Critical Care
Volume21
Issue number2
DOIs
Publication statusPublished - 1 Jun 2006
Externally publishedYes

Keywords

  • Blood glucose
  • Glucose control
  • Hyperglycemia
  • Insulin
  • Intensive care

Cite this

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title = "Blood glucose on day of intensive care unit admission as a surrogate of subsequent glucose control in intensive care",
abstract = "Purpose: The aim of the study was to test whether the mean of the highest and lowest glucose values on day 1 (Glu1) is a useful surrogate marker of mean blood glucose during the totality of intensive care unit (ICU) stay (Glutot). Materials and Methods: Glutot values were extracted from electronically stored biochemical databases (point-of-care laboratory) and Glu1 values from electronically stored prospectively collected patient databases in ICUs of 4 hospitals from January 2000 to October 2004. Statistical assessment of relationship between Glu1 and Glutot was done. Results: There were 197 227 blood glucose measurements for 8039 patients. The average of all blood glucose measurements was 8.22 ± 2.75 mmol/L. The difference between the average of all glucose values (N = 197 227) and average of Glu1 (n = 8039) was 0.17 mmol/L. This difference in each hospital was also small (0.26, -0.13, 0.12, and 0.37 mmol/L, respectively). Conclusions: Glu1 was a good predictor of Glutot across all study hospitals. This observation makes it possible to use Glu1 as a surrogate of glucose control during ICU stay and opens the door to understanding ICU glucose control across the whole of Australia and New Zealand.",
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Blood glucose on day of intensive care unit admission as a surrogate of subsequent glucose control in intensive care. / Egi, Moritoki; Bellomo, Rinaldo; Stachowski, Eddie; French, Craig J.; Hart, Graeme; Stow, Peter.

In: Journal of Critical Care, Vol. 21, No. 2, 01.06.2006, p. 197-202.

Research output: Contribution to journalArticleResearchpeer-review

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