Abstract
Purpose: The aim of the study was to test whether the mean of the highest and lowest glucose values on day 1 (Glu1) is a useful surrogate marker of mean blood glucose during the totality of intensive care unit (ICU) stay (Glutot). Materials and Methods: Glutot values were extracted from electronically stored biochemical databases (point-of-care laboratory) and Glu1 values from electronically stored prospectively collected patient databases in ICUs of 4 hospitals from January 2000 to October 2004. Statistical assessment of relationship between Glu1 and Glutot was done. Results: There were 197 227 blood glucose measurements for 8039 patients. The average of all blood glucose measurements was 8.22 ± 2.75 mmol/L. The difference between the average of all glucose values (N = 197 227) and average of Glu1 (n = 8039) was 0.17 mmol/L. This difference in each hospital was also small (0.26, -0.13, 0.12, and 0.37 mmol/L, respectively). Conclusions: Glu1 was a good predictor of Glutot across all study hospitals. This observation makes it possible to use Glu1 as a surrogate of glucose control during ICU stay and opens the door to understanding ICU glucose control across the whole of Australia and New Zealand.
Original language | English |
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Pages (from-to) | 197-202 |
Number of pages | 6 |
Journal | Journal of Critical Care |
Volume | 21 |
Issue number | 2 |
DOIs | |
Publication status | Published - 1 Jun 2006 |
Externally published | Yes |
Keywords
- Blood glucose
- Glucose control
- Hyperglycemia
- Insulin
- Intensive care