Bioorthogonal hydrogels by thiol–halide click crosslinking with fast gelation time and tunable stability in aqueous media

Vinh X. Truong, Ilze Donderwinkel, Jessica E. Frith

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12 Citations (Scopus)


Thiol‐halide click reaction is utilized in polymer crosslinking to form hydrogels with tailored rate of disintegration suitable. The crosslinking process is bioorthogonal, which allows for encapsulation of living cells for three‐dimensional cell culture study.
Original languageEnglish
Pages (from-to)1872-1876
Number of pages5
JournalJournal of Polymer Science, Part A: Polymer Chemistry
Issue number18
Publication statusPublished - 15 Sept 2019


  • biocompatibility
  • bioorthogonal click
  • cell-laden hydrogels
  • degradation
  • fibroblast
  • mesenchymal stem cell
  • thiol–bromo click
  • thiol–iodo click

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