Bioorthogonal hydrogels by thiol–halide click crosslinking with fast gelation time and tunable stability in aqueous media

Vinh X. Truong; Ilze Donderwinkel; Jessica E. Frith

doi:10.1002/pola.29267

Bioorthogonal hydrogels by thiol–halide click crosslinking with fast gelation time and tunable stability in aqueous media

Vinh X. Truong, Ilze Donderwinkel, Jessica E. Frith

Materials Science & Engineering

Research output: Contribution to journal › Article › Research › peer-review

13 Citations (Scopus)

Abstract

Thiol‐halide click reaction is utilized in polymer crosslinking to form hydrogels with tailored rate of disintegration suitable. The crosslinking process is bioorthogonal, which allows for encapsulation of living cells for three‐dimensional cell culture study.

Original language	English
Pages (from-to)	1872-1876
Number of pages	5
Journal	Journal of Polymer Science, Part A: Polymer Chemistry
Volume	57
Issue number	18
DOIs	https://doi.org/10.1002/pola.29267
Publication status	Published - 15 Sept 2019

Keywords

biocompatibility
bioorthogonal click
cell-laden hydrogels
degradation
fibroblast
mesenchymal stem cell
thiol–bromo click
thiol–iodo click

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title = "Bioorthogonal hydrogels by thiol–halide click crosslinking with fast gelation time and tunable stability in aqueous media",

abstract = "Thiol‐halide click reaction is utilized in polymer crosslinking to form hydrogels with tailored rate of disintegration suitable. The crosslinking process is bioorthogonal, which allows for encapsulation of living cells for three‐dimensional cell culture study.",

keywords = "biocompatibility, bioorthogonal click, cell-laden hydrogels, degradation, fibroblast, mesenchymal stem cell, thiol–bromo click, thiol–iodo click",

author = "Truong, {Vinh X.} and Ilze Donderwinkel and Frith, {Jessica E.}",

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AU - Truong, Vinh X.

AU - Donderwinkel, Ilze

AU - Frith, Jessica E.

PY - 2019/9/15

Y1 - 2019/9/15

N2 - Thiol‐halide click reaction is utilized in polymer crosslinking to form hydrogels with tailored rate of disintegration suitable. The crosslinking process is bioorthogonal, which allows for encapsulation of living cells for three‐dimensional cell culture study.

AB - Thiol‐halide click reaction is utilized in polymer crosslinking to form hydrogels with tailored rate of disintegration suitable. The crosslinking process is bioorthogonal, which allows for encapsulation of living cells for three‐dimensional cell culture study.

KW - biocompatibility

KW - bioorthogonal click

KW - cell-laden hydrogels

KW - degradation

KW - fibroblast

KW - mesenchymal stem cell

KW - thiol–bromo click

KW - thiol–iodo click

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DO - 10.1002/pola.29267

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JO - Journal of Polymer Science, Part A: Polymer Chemistry

JF - Journal of Polymer Science, Part A: Polymer Chemistry

IS - 18

ER -

Bioorthogonal hydrogels by thiol–halide click crosslinking with fast gelation time and tunable stability in aqueous media

Abstract

Keywords

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