Biomolecular sensing using gold nanoparticle-coated ZnO nanotetrapods

Ramakrishna Podila, Pengyu Chen, Jason Reppert, Apparao M. Rao, Pu Chun Ke

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7 Citations (Scopus)


Gold nanoparticle-coated ZnO tetrapods have been utilized as a substrate for the detection of fluorescently labeled protein tetramethylrhodamine isothiocyanate bovine serum albumin and phospholipid 1,2-dipalmitoyl-sn-glycero- 3-phosphoethanolamine-N-(Lissamine rhodamine B sulfonyl) down to the concentrations of 15 pM and 79 nM, respectively. Our detection scheme is based on enhanced fluorescence excitation of the biomolecular analytes by the surface plasmon polaritons of gold nanoparticles coated on the ZnO tetrapod whiskers. This enhanced excitation is confirmed using COMSOL Multiphysics, where the optical near field is shown to be dependent on the coating density of the gold nanoparticles and branching of the ZnO nanostructures.

Original languageEnglish
Pages (from-to)2328-2333
Number of pages6
JournalJournal of Materials Research
Issue number17
Publication statusPublished - 28 Aug 2011
Externally publishedYes


  • Biological
  • Nanostructure
  • Sensor

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