Abstract
In this chapter, we discuss the motivation for studying transport phenomena in the human body using computational simulation techniques. We present a selection of methodologies that are representative of the strengths that such an approach offers, as well as emerging trends for such techniques. Inevitably, within the confines of a single chapter, we had to be selective, both regarding the target organs and diseases and the actual computational techniques we present. For the former, the selection was based on societal impact: cardiovascular diseases are the principal cause for mortality worldwide and as such the impetus for enhancing our understanding and improving diagnosis and treatment for such diseases is particularly emphasized. Regarding the selection of techniques, we focused not only on approaches that exemplify the versatility and variety that computer modeling presents us with but also on newer trends that seem to be particularly promising for extending the reach and value of such methodologies.
| Original language | English |
|---|---|
| Title of host publication | Comprehensive Biotechnology |
| Editors | Murray Moo-Young |
| Place of Publication | Netherlands |
| Publisher | Elsevier |
| Chapter | 5 |
| Pages | 18-31 |
| Number of pages | 14 |
| Volume | 5 |
| Edition | 3rd |
| ISBN (Electronic) | 9780444640475 |
| ISBN (Print) | 9780444640468 |
| DOIs | |
| Publication status | Published - 2019 |
| Externally published | Yes |
Keywords
- Aneurysm
- Atherosclerosis
- Biofluids
- Cardiovascular disease
- Computational fluid dynamics computational modeling
- Dissection
- Simulation
- Stroke
- Thrombosis
- Transport phenomena
- Wall shear stress
