Biological activities and therapeutic effects of Celastrus paniculatus seed oil

Kim Wei Chan, Voon Kin Chin, Norsharina Ismail, Der Jiun Ooi, Nicholas M.H. Khong, Norhaizan Mohd Esa

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

1 Citation (Scopus)


Celastrus paniculatus, commonly known as the “Intellect Tree, " or vernacularly known as “Malkangni” and “Jyotishmati, " is a medicinal plant that native to the India continent. Traditionally, Celastrus paniculatus seed oil (CPSO) is valued for its beneficial properties against neurological disorders in the Ayurvedic medicine. Findings from the modern scientific research show that CPSO was high in oleic acid and containing various bioactive compounds, such as phytosterols, tocopherols, etc. Additionally, CPSO was reported to exhibit multiple biological activities and therapeutic effects in different experimental models, particularly on its neuroprotective properties. Nevertheless, in-depth studies on the toxicity of CPSO, as well as the structure-bioactivity relationships of its bioactive compounds are scarce. Thus it is recommended that these aspects should be highlighted in the future studies of CPSO, in order to produce a range of safe and standardized CPSO-based nutraceutical products/herbal medicines with consistent and reliable therapeutic effects.

Original languageEnglish
Title of host publicationMultiple Biological Activities of Unconventional Seed Oils
EditorsAbdalbasit Adam Mariod
Place of PublicationUnited Kingdom
Number of pages13
ISBN (Electronic)9780128241356
ISBN (Print)9780323903264
Publication statusPublished - 2022


  • Biological activity
  • Celastrus paniculatus
  • Jyothismati
  • Malkangni
  • Seed oil
  • Therapeutic effect

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