Biological activities and phytochemicals of Swietenia macrophylla king

Soheil Zorofchian Moghadamtousi, Bey Hing Goh, Chim Kei Chan, Tara Shabab, Habsah Abdul Kadir

Research output: Contribution to journalArticleResearchpeer-review

47 Citations (Scopus)

Abstract

Swietenia macrophylla King (Meliaceae) is an endangered and medicinally important plant indigenous to tropical and subtropical regions of the World. S. macrophylla has been widely used in folk medicine to treat various diseases. The review reveals that limonoids and its derivatives are the major constituents of S. macrophylla. There are several data in the literature indicating a great variety of pharmacological activities of S. macrophylla, which exhibits antimicrobial, anti-inflammatory, antioxidant effects, antimutagenic, anticancer, antitumor and antidiabetic activities. Various other activities like anti-nociceptive, hypolipidemic, antidiarrhoeal, anti-infective, antiviral, antimalarial, acaricidal, antifeedant and heavy metal phytoremediation activity have also been reported. In view of the immense medicinal importance of S. macrophylla, this review aimed at compiling all currently available information on its ethnomedicinal uses, phytochemistry and biological activities of S. macrophylla, showing its importance.

Original languageEnglish
Pages (from-to)10465-10483
Number of pages19
JournalMolecules
Volume18
Issue number9
DOIs
Publication statusPublished - Sep 2013
Externally publishedYes

Keywords

  • Biological activity
  • Limonoids
  • Mahogany
  • Phytochemicals
  • Swietenia macrophylla

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