TY - JOUR
T1 - Bioinspired nervous signal transmission system based on two-dimensional laminar nanofluidics
T2 - from electronics to ionics
AU - Teng, Yunfei
AU - Liu, Pei
AU - Fu, Lin
AU - Kong, Xiang-Yu
AU - Jiang, Lei
AU - Wen, Liping
N1 - Funding Information:
ACKNOWLEDGMENTS. We thank Dr. Jinlei Yang for useful support and discussions. This work was supported by the National Key R&D Program of China (Grants 2017YFA0206904 and 2017YFA0206900), National Natural Science Foundation of China (Grants 21625303, 21905287, 51673206, and 21988102), Beijing Natural Science Foundation (Grant 2194088), Strategic Priority Research Program of the Chinese Academy of Sciences (Grant XDA2010213), and the Key Research Program of the Chinese Academy of Sciences (Grant QYZDY-SSW-SLH014).
Publisher Copyright:
© 2020 National Academy of Sciences. All rights reserved.
PY - 2020/7/21
Y1 - 2020/7/21
N2 - Mammalian nervous systems, as natural ionic circuitries, stand out in environmental perception and sophisticated information transmission, relying on protein ionic channels and additional necessary structures. Prosperously emerged ionic regulated biomimetic nanochannels exhibit great potentialities in various application scenarios, especially signal transduction. Most reported direct current systems possess deficiencies in informational density and variability, which are superiorities of alternating current (AC) systems and necessities in bioinspired nervous signal transmission. Here, inspired by myelinated saltatory conduction, alternating electrostatic potential controlled nanofluidics are constructed with a noncontact application pattern and MXene nanosheets. Under time-variant external stimuli, ions confined in the interlaminar space obtain the capability of carriers for the AC ionic circuit. The transmitted information is accessible from typical sine to a frequency-modulated binary signal. This work demonstrates the potentiality of the bioinspired nervous signal transmission between electronics and ionic nanofluidics, which might push one step forward to the avenue of AC ionics.
AB - Mammalian nervous systems, as natural ionic circuitries, stand out in environmental perception and sophisticated information transmission, relying on protein ionic channels and additional necessary structures. Prosperously emerged ionic regulated biomimetic nanochannels exhibit great potentialities in various application scenarios, especially signal transduction. Most reported direct current systems possess deficiencies in informational density and variability, which are superiorities of alternating current (AC) systems and necessities in bioinspired nervous signal transmission. Here, inspired by myelinated saltatory conduction, alternating electrostatic potential controlled nanofluidics are constructed with a noncontact application pattern and MXene nanosheets. Under time-variant external stimuli, ions confined in the interlaminar space obtain the capability of carriers for the AC ionic circuit. The transmitted information is accessible from typical sine to a frequency-modulated binary signal. This work demonstrates the potentiality of the bioinspired nervous signal transmission between electronics and ionic nanofluidics, which might push one step forward to the avenue of AC ionics.
KW - AC system
KW - Biomimetic structures
KW - Information transmission
KW - Ion transportation
KW - Nanofluidics
UR - https://www.scopus.com/pages/publications/85088881821
U2 - 10.1073/pnas.2005937117
DO - 10.1073/pnas.2005937117
M3 - Article
C2 - 32611809
AN - SCOPUS:85088881821
SN - 0027-8424
VL - 117
SP - 16743
EP - 16748
JO - Proceedings of the National Academy of Sciences of the United States of America
JF - Proceedings of the National Academy of Sciences of the United States of America
IS - 29
ER -